Swapna MenonJan 27

#RosalindFranklin: 37 years of life. 16 years of science.
Beyond DNA. Beyond the lost #Nobel Prize or two(?)
Her #XrayCrystallography ignited:
• Carbon chemistry & fuel efficiency
• Seeds of #MolecularBiology and genomics
• Foundations of structural #virology

Full story here:

https://medium.com/the-quantastic-journal/rosalind-franklin-a-short-life-lasting-contributions-to-dna-structure-and-structural-virology-4acc949eea8c

#WomenInSTEM #SciComm #ScienceHistory #QotoOrg #Histodon

@[email protected] @[email protected] @[email protected]

Swapna MenonJan 21

#RosalindFranklin Life of 37 years. 16 in science. 2 unraveling DNA.

1950s #XRayCrystallography No easy feat.

DNA story, #NobelPrize clashes, gender barriers. #ScienceHistory

Other XRC pioneer women. #WomenInSTEM

https://medium.com/the-quantastic-journal/rosalind-franklin-a-short-life-lasting-contributions-to-dna-structure-and-structural-virology-4acc949eea8c

#MolecularBiology #SciComm #FediScience #QotoOrg

@[email protected] @[email protected] @[email protected]

Uni GöttingenDec 18

How do enzymes, nature's highly efficient catalysts, achieve almost perfect precision and efficiency?

This is the research question to be addressed by newly funded project in chemistry: “NEXT - Quantum Biology”. The funding will strengthen #interdisciplinary teams and bridge #StructureBiology and #QuantumPhysics.

Congratulations to researchers at our Uni, MPI-NAT in Göttingen, and Hamburg Uni: www.uni-goettingen.de/en/3240.html?id=8028. With thanks to the Volkswagen Foundation.

#Chemistry #QuantumBiology #XrayCrystallography

StructBiolCommunicationsJul 14, 2025
Features of sample preparation that should be considered prior to biomolecular crystallization experiments are reviewed, as described in the SAMPREP workshop during the 73rd Annual ACA Meeting #Crystallization #XRayCrystallography #StructuralBiology https://doi.org/10.1107/S2053230X25004650
StructBiolCommunicationsJun 24, 2025
The structure of the C1 domain of the surface-layer protein SlpM from L. brevis provides new insights into the architecture and evolutionary adaptability of SLPs in Lactobacillus species #XRayCrystallography #SurfaceLayerProtein #SlpM https://doi.org/10.1107/S2053230X25004194
jobRxivDec 22, 2024

Postdoctoral Scholar-Structural Biology in Protein Dynamics

Icahn School of Medicine at Mount Sinai

Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!

See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89569

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jobRxiv
jobRxivDec 15, 2024

Postdoctoral Scholar-Structural Biology in Protein Dynamics

Icahn School of Medicine at Mount Sinai

Join our lab as a #StructuralBiology #Postdoc to study proteins in #Alzheimers & #Cancer using #CryoEM & #XrayCrystallography at Mount Sinai!

See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-scholar-structural-biology-in-protein-dynamics-2/?feed_id=89072

Science Jobs - Find science and research jobs - 2,801 jobs

The international job board for scientists, by scientists. Find science jobs in academia or industry: MSc, PhD, Postdoc, Scientist, Faculty and more!

jobRxiv
StructBiolCommunicationsNov 11, 2024
Unlike other serpins, human serpin B9 shows significant structural deviations around helix D, with a larger surface cavity, which could serve as a promising target for small-molecule inhibitors #Serpins #XRayCrystallography #Crystallization https://t.co/ilB7Aa3Krg
Crystallization and crystallographic studies of human serine protease inhibitor (serpin) B9

This study successfully determined the crystal structure of human serpin B9 at 1.9 Å resolution and identified notable structural differences surrounding helix D, providing a potential target for the development of anticancer therapeutics.

Acta Crystallographica Section F
StructBiolCommunicationsOct 14, 2024
This topical review focuses on 13 X-ray crystal structures and five electron cryo-microscopy structures of glucose-6-phosphate dehydrogenase in the PDB #Glucose6PhosphateDehydrogenase #XRayCrystallography #ElectronCryoMicroscopy https://doi.org/10.1107/S2053230X24008112
Glucose-6-phosphate dehydrogenase and its 3D structures from crystallography and electron cryo-microscopy

An investigation of different types of glucose-6-phosphate dehydrogenase (G6PD) is reported, including NAD+- and NADP+-dependent G6PDs, fused glucose-6-phosphate dehydrogenase–6-phosphogluconolactonase and bacterial F420-dependent G6PD. An extensive data-review tabulation of PDB entries is also provided for both X-ray crystal and electron cryo-microscopy structures.

Acta Crystallographica Section F
StructuralBiologyOct 9, 2024
A method is presented to robustly exclude erroneous reflection measurements arising from beamstop shadows in crystallographic diffraction experiments #XRayCrystallography #AUSPEX #Outliers https://doi.org/10.1107/S2059798324008519
Robust and automatic beamstop shadow outlier rejection: combining crystallographic statistics with modern clustering under a semi-supervised learning strategy

Beamstops and beamstop shadows can lead to erroneous reflection measurements in crystallographic diffraction experiments, which is a common problem in data processing. Here, a method is presented that combines crystallographic statistics with machine learning to robustly detect such reflections.

Acta Crystallographica Section D