"Ergebnisse deuten darauf hin, dass die Subtypen #H3N1 #H4N6 #H5N2 #H5N3 #H6N2 & #H11N9 hohes Potenzial für zukünftige Ausbreitung haben. Darüber hinaus besteht bei den Subtypen #H5N1 #H5N6 #H5N8 & #H9N2 erhebliches Risiko für erneutes Auftreten. Außerdem hat unsere Analyse 12 H9N2-Schlüsselstämme als interne genetische Spender für die Anpassung der AIV an den Menschen hervorgehoben, was die entscheidende Rolle von H9N2 bei der Erleichterung der #AIV -Übertragung zeigt"
https://etidiohnew.blogspot.com/2025/03/early-warning-signals-and-role-of-h9n2.html
#Genetic #diversity of highly pathogenic avian #influenza #H5N6 and #H5N8 viruses in #poultry #markets in #Guangdong, #China, 2020-2022
Source: Journal of Virology, ABSTRACTH5 highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 (Gs/Gd) lineage continue to evolve and cause outbreaks in domestic poultry and wild birds, with sporadic spillover infections in mammals. The global spread of clade 2.3.4.4b viruses via migratory birds since 2020 has…
Source: Journal of Virology, ABSTRACTH5 highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/96 (Gs/Gd) lineage continue to evolve and cause outbreaks in domestic poultry and…
#Phylogenetic Characterization of Novel #Reassortant 2.3.4.4b #H5N8 Highly Pathogenic Avian #Influenza Viruses Isolated from Domestic #Ducks in #Egypt During the Winter Season 2021–2022
Source: Viruses, AbstractAvian influenza (AI) is an extremely contagious viral disease of domestic and wild birds that can spread rapidly among bird populations, inducing serious economic losses in the poultry industry. During the winter season 2021–2022, we isolated seventeen highly…
Source: Viruses, AbstractAvian influenza (AI) is an extremely contagious viral disease of domestic and wild birds that can spread rapidly among bird populations, inducing serious economic losses in…
#GENETIC #FEATURES OF AVIAN #INFLUENZA (A/ #H5N8) CLADE 2.3.4.4B ISOLATED FROM #QUAIL IN #EGYPT
Source: Virus Research, AbstractSeveral genotypes of the highly pathogenic avian influenza (HPAI) virus H5N8 subtype within clade 2.3.4.4b continue to circulate in different species of domestic birds across Egypt. It is believed that quail contribute to virus replication and adaptation to other gallinaceous poultry species and humans. This study provides genetic…
Source: Virus Research, AbstractSeveral genotypes of the highly pathogenic avian influenza (HPAI) virus H5N8 subtype within clade 2.3.4.4b continue to circulate in different species of domestic bir…
Complex Evolutionary #Dynamics of #H5N8 #Influenza A Viruses Revealed by Comprehensive #Reassortment #Analysis
Source: Viruses, AbstractInfluenza A viruses (IAVs) circulate among different species and have the potential to cause significant pandemics in humans. This study focuses on reassortment events in the H5N8 subtype of IAV, which poses a serious threat to public health due to its high pathogenicity in birds and potential for cross-species transmission. We…
Source: Viruses, AbstractInfluenza A viruses (IAVs) circulate among different species and have the potential to cause significant pandemics in humans. This study focuses on reassortment events in t…
Complex Evolutionary #Dynamics of #H5N8 #Influenza A Viruses Revealed by Comprehensive #Reassortment Analysis https://www.mdpi.com/1999-4915/16/9/1405
This detailed case study of specific H5N8 viruses revealed previously undescribed reassortment events, highlighting the complex evolutionary history and potential pandemic threat of H5N8 IAVs.
Influenza A viruses (IAVs) circulate among different species and have the potential to cause significant pandemics in humans. This study focuses on reassortment events in the H5N8 subtype of IAV, which poses a serious threat to public health due to its high pathogenicity in birds and potential for cross-species transmission. We retrieved 2359 H5N8 IAV sequences from GISAID, and filtered and analyzed 442 complete genomic sequences for reassortment events using pairwise distance deviation matrices (PDDMs) and pairwise distance correspondence plots (PDCPs). This detailed case study of specific H5N8 viruses revealed previously undescribed reassortment events, highlighting the complex evolutionary history and potential pandemic threat of H5N8 IAVs.
Novel #Genotype of #HA Clade 2.3.4.4b #H5N8 Subtype High Pathogenicity Avian #Influenza Virus Emerged at a Wintering Site of Migratory #Birds in #Japan, 2021/22 Winter https://pubmed.ncbi.nlm.nih.gov/38787232/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1LGAx__djGAJ9poBzWGqPtjEbBDtz4ipSRRPUplmgHEyyF_Ihj&fc=None&ff=20240524150849&v=2.18.0.post9+e462414
Our results directly demonstrate the emergence of a novel genotype of H5N8 HPAIV through gene reassortment at a wintering site.
Surveillance of avian influenza virus (AIV) was conducted in the 2021-2022 winter season at a wintering site of migratory <i>Anatidae</i> in Japan. An H5N8 subtype high pathogenicity AIV (HPAIV) with a unique gene constellation and four low pathogenicity AIVs (LPAIVs) were isolated from environmenta …