Rett syndrome is a severe developmental disorder triggered by mutations in the MECP2 gene, which researchers have recently discovered compromises the structural integrity of developing brain blood vessels. This #genetic mutation causes the overexpression of a specific #microRNA that breaks down the tight seals of the blood-brain barrier, resulting in vascular leakiness that disrupts neural function.
#Neuroscience #CellBiology #Genetics #sflorg
https://www.sflorg.com/2026/03/ns03142601.html
Scientists discover genetics behind leaky brain blood vessels in Rett syndrome

By showing the problem derives from genetic mutations that lead to overexpression of a microRNA, MIT researchers’ study points to potential treatment.

13-Mar-2026
New study clarifies how #temperature shapes sex #development in leopard #gecko
Researchers pinpoint when temperature determines sex and uncover early #genetic changes guiding male or female development in leopard gecko https://www.eurekalert.org/news-releases/1119619 #science
New study clarifies how temperature shapes sex development in leopard gecko

Researchers have long known that temperature can determine whether some reptiles develop as male or female, but this process is not well understood in lizards and snakes. A new study in leopard geckos offers the first detailed look at how this works in a squamate reptile. The researchers found that differences between males and females begin at the genetic level before any physical changes appear and identified the key developmental window when temperature decides sex.

EurekAlert!

Wer mit dem #mdrza unterwegs ist sieht auch mal ein schneeweißes #Wild

Leider fürs #smartphone zu weit weg um es besser hinzubekommen.

Wer genau hinsieht, sieht die dunklen daneben.

#natur #genetic #albino #radfahren #rad #fahrradbubble #Fahrradfahren #radsport #Fedibikes

#SpiderSilk-making organs evolved due to a 400-million-year-old #genetic oops
#Spiders and silk go hand in hand, but spinnerets may exist thanks to an ancient error
A close look at the genetics and development of #spinnerets — spiders’ silk-making organs — reveals that an early arachnid doubled all of its DNA hundreds of millions of years ago. The findings suggest key, doubled genes were responsible for the #evolution of spinnerets.
https://www.sciencenews.org/article/spider-silk-making-organ-evolve-genetic
https://archive.ph/LVsPW
Spider silk-making organs evolved due to a 400-million-year-old genetic oops

An ancient ancestor of spiders and relatives doubled its genome about 400 million years ago, setting the stage for the evolution of spinnerets.

Science News
https://www.theguardian.com/society/2026/mar/04/scientists-drug-children-zorevunersen-epilepsy-dravet; https://www.dravet.org.uk/; https://www.nejm.org/doi/full/10.1056/NEJMoa2506295 (abstract only). "The lead author Helen Cross... said: 'I regularly see #patients with hard-to-treat #genetic #epilepsies, who can have multiple #seizures a week. Many are unable to do anything independently for themselves; they require around the clock care & are at high risk of sudden unexpected death in #epilepsy [SUDEP].” This is very good news.
Scientists laud life-changing drug for children with resistant form of epilepsy

Preliminary trials into Zorevunersen find drug to be safe and well tolerated by those with Dravet syndrome

The Guardian

Bush #bee #hives are dying & #beekeepers challenged as #treatment-resistant #varroa mites spread.

#Genetic #testing has confirmed that some of the #parasites are #mutating.

Beekeepers are being urged to rotate chemical treatments to slow the pace of resistance. #auspol #apiarists

https://www.abc.net.au/news/rural/2026-03-04/varroa-mite-treatment-chemical-resistance-bees/106409956

Treatment-resistant varroa mites spread in Queensland and New South Wales

The world's worst honey bee parasite is genetically mutating, making it resistant to common treatments used to save hives.

🧪This tissue culture-based #genetic transformation system in #soybean significantly enhances transformation efficiency, shortens the transformation cycle, and demonstrates broad #genotype independence.
🔗 https://doi.org/10.1111/jipb.70102
@WileyLifeSci
#PlantScience #agtech #CropScience
🌾Cold temps impact every aspect of #rice #growth (#relatable, ngl🥶❄️)
🔎Guo et al. explore the breeding potential of cold-tolerant #genes, providing a strategic framework to advance #genetic improvement of cold tolerance.
🔗https://doi.org/10.1111/jipb.70086
@WileyLifeSci
#PlantSci #crop #botany

Have we leapt into commercial #genetic testing without understanding it?

Daphne O. Martschenko and Sam Trejo both want to make the world a better, fairer, more equitable place. But they disagree on whether studying social #genomics —elucidating any potential genetic contributions to behaviors ranging from mental illnesses to educational attainment to #political affiliation—can help achieve this goal.
#dna #privacy

https://arstechnica.com/science/2026/02/have-we-leapt-into-commercial-genetic-testing-without-understanding-it/

Have we leapt into commercial genetic testing without understanding it?

A new book argues that tests might reshape human diversity even if they don't work.

Ars Technica