Olusanya et al. study genetic load and extinction in a metapopulation. Their analysis is based on a novel theoretical framework that tracks the co-evolution of load and population sizes and gives a nuanced picture of the genetic and demographic factors that affect extinction. Now available ahead of print! https://www.journals.uchicago.edu/doi/10.1086/735562

#genetic #geneticLoad #extinction #metapopulation #coevolution #population

Our extensively revised preprint now goes beyond clarifying Haldane’s arguments about the #CostOfSelection / #SubstitutionalLoad / #SelectiveDeaths, it also significantly extends them, and applies the resulting model to data https://www.biorxiv.org/content/10.1101/2021.11.01.466728v2
@jdmatheson @moi #EvolgenPaper #PopulationGenetics #NaturalSelection #FitnessComponents #GeneticLoad 1/10