Try out our integration of the amazing protein structure search tool #Foldseek on #SubtiWiki (https://subtiwiki.uni-goettingen.de/v5/foldseek)! Just upload a structure or use PDB/AlphaFoldDB entries to find similar structures. @imprsgs @unigoettingen
#alphafold #bacillus #subtilis
SubtiWiki

“Recognized by nearly 50 citations since its publication, this work has significantly contributed to the field of life science (…).”

🥁 That’s what the committee said about this work, one of the #SIBRemarkableOutputs 2023 👏

👉 https://tinyurl.com/yhe3n2mm

#Foldseek #AlphaFoldDB

Discover the SIB Remarkable Outputs 2023

Staying abreast of the latest advances and bright ideas emerging in a field as diverse as bioinformatics is challenging. The SIB Remarkable Outputs provide the global community with a shortlist of out...

Structural phylogenetics -- a great preprint now out by Dave Moi et al, describing their elegant approach and implementation.

We were very lucky to be able to work with Foldtree, and Dave, on our recent 7TMIC paper, prior to Foldtree's release. We found it very informative when working with an extremely difficult protein superfamily!

https://www.biorxiv.org/content/10.1101/2023.09.19.558401v2

#phylogenetics #alphafold #foldseek #bioinformatics #evolution

Very nice #preprint by Ruperti et al (Arendt lab) combining #AlphaFold and #Foldseek with #SingleCell #RNAseq to improve annotation of #sponge Spongilla lacustris genes: https://www.biorxiv.org/content/10.1101/2022.07.05.498892v2
(not very new but just read it)

RT@[email protected] Martin Steinegger:

#Foldseek's webserver now allows predicting #structures thanks to the great #ESMfold API. Just paste an amino acid sequence, click "PREDICT STRUCTURE" and search against structures from #ESMatlas, #AlphaFoldDB, #PDB & more. Work by @milot_mirdita
. Check it out at http://search.foldseek.com

It does not stop to amaze me what type of analyses you now have at your fingertips!

Foldseek Search Server

Foldseek Server offers fast and sensitive protein structure alignments against large protein structure collections