Researchers have identified a critical structural boundary within the immune-regulating gene RELA—specifically at amino acid proline 290 (P290)—that dictates how genetic mutations manifest in patients with a rare inherited inflammatory disease.
#MolecularGenetics #Immunology #ClinicalPathology #sflorg
https://www.sflorg.com/2026/05/imgy05222601.html
RELA Gene Boundary & Rare Inflammatory Disease

Discover how identifying the RELA gene P290 boundary helps predict disease severity and guides treatments for rare autoinflammatory conditions.

📚 Done with #AnatomicalPathology boards and now gotta cram for #ClinicalPathology boards next week.

"I love the visual aspect of pathology. What we see under the microscope is so beautiful." - Jiani Chai, MD, PhD, #pathology chief resident & #immunology researcher at Montefiore Einstein.

Read Dr. Chai's #path2pathology at http://tinyurl.com/4dhz2v6p

#pathologists #immunology #biomarkers #hematology #genetics #hematologyoncology #diagnosticpathology #clinicalpathology #pathologyresidents #residency

Diagnosing and Researching Diseases: Jiani Chai, MD, PhD, Pathology Chief Resident | Albert Einstein College of Medicine

Jiani Chai, MD, PhD, Pathology PGY-3 and Chief Resident

Albert Einstein College of Medicine