From Lab Bench to Browser: A Hybrid Digital Twin for CHO Cell Culture

I rebuilt two published CHO cell-culture papers — a hybrid ODE + machine-learning growth model, and a genome-scale metabolic reduction pipeline — as an interactive digital twin that runs in the browser. Here's how it works, what's under the hood, and an honest take on what it's good for. No hosted version yet; the code is on GitHub and a live instance is coming soon.

https://kemal.yaylali.uk/cho-cell-culture-digital-twin-browser/

🧪 Could digital modeling redefine how we grow CHO cells for biologics?

🔗 Wheels turning: CHO cell modeling moves into a digital biomanufacturing era. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.06.035

📚 CSBJ: https://www.csbj.org/

#Biomanufacturing #CHOCells #DigitalTwins #BiotechInnovation #DigitalBiomanufacturing #Bioprocessing #Biologics #CellCulture #GenomeScaleModels #SmartManufacturing #BiopharmaInnovation #SystemsBiology #Biotechnology #Bioinformatics

Cytion is a leading biotechnology company dedicated to advancing cell culture technologies. By providing high-quality, contamination-free cell cultures, expert training, and innovative solutions, Cytion helps researchers achieve reliable and reproducible results.

https://www.linkedin.com/company/cytion/

#Cytion #VeroCells #JurkatCells #ChoCells #mda-mb-231 #u2os cells #sh-sy5y #hepg2 cells

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Cytion | 342 followers on LinkedIn. Advancing Research, Cell by Cell | At Cytion, we are dedicated to being your trusted partner in cell culture solutions. As a leading cell bank, we specialize in providing high-quality, contamination-free cells from both human and animal origins. Our rigorous quality control and authentication processes ensure that researchers and scientists can rely on our cell lines for their genetic authenticity and reliability.