Qing Nie
System learning of single cells
Fascinating talk about analyses of single cell data
Eg paper on angiogenesis in #elife
"Spatial–temporal order–disorder transition in angiogenic NOTCH signaling controls cell fate specification"
#ScRNA #cellchat #rna #notch #cellbiology
https://elifesciences.org/articles/89262
https://faculty.sites.uci.edu/qnie/
COMMOT, COMMunication analysis by Optimal Transport, a versatile tool infer cell–cell communication in #SpatialTranscriptomics 🤠
Compatible with #MERFISH #Visium seqFISH+ #STARmap
vs #CellChat #Giotto #CellPhoneDBv3
Dr. Qing Nie lab Nature Methods 2023
https://www.nature.com/articles/s41592-022-01728-4
Screening cell–cell communication in spatial transcriptomics via collective optimal transport - Nature Methods
This work presents a computational framework, COMMOT, to spatially infer cell–cell communication from transcriptomics data based on a variant of optimal transport (OT).
Charrvein
Hao Yin