🔬 Spatial Transcriptomics - Feb 2026
• CLIM-TIME maps 7 TME subtypes linked to T cell therapy response
• Kupffer cells promote immune evasion in liver metastases
• CD276 drives chemoresistance in pancreatic cancer
• T cell activation correlates with better survival in glioblastoma
• mFISH3D visualizes multiple mRNA types in intact mouse brains
• RNA-modifying proteins emerge as potential therapeutic targets
🧬 How can AI bridge the gap between histology and spatial transcriptomics?
🔗 SegDecon bridges histology and transcriptomics through AI-based nuclei segmentation and image-informed spatial deconvolution. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.10.041
📚 CSBJ: https://www.csbj.org/
#SpatialTranscriptomics #Histology #Genomics #SystemsBiology #NucleiSegmentation #AI #CellBiology #TissueBiology #Bioimaging
Is spatial transcriptomics data preprocessing giving you a headache? You're not alone! 🤯
Join our webinar designed for new researchers to simplify the complex world of image-based spatial omics. We'll walk through the practical workflow step-by-step, from initial cell segmentation to cleaning up your data.
Get the foundational skills you need. 📅 Sign up here: https://t1p.de/lqbg1
#Transcriptomics #SpatialTranscriptomics #Omics #DataScience #ResearchWebinar #GHGA #ELIXIR #deNBI
Celltrion has entered a joint R&D agreement with Portrai to leverage spatial transcriptomics and AI for new drug discovery, securing exclusive rights to up to 10 targets in a deal worth up to $87.75 million, with additional royalties upon commercialization.
Decoding cell–cell communication using spatial transcriptomics
#spatialtranscriptomics #omics #ccc
https://www.nature.com/articles/s41576-025-00824-3
In this Tools of the Trade article, Ankit Agrawal introduces the computational framework NiCo (Niche Covariation), which integrates spatial transcriptomics with single-cell RNA-sequencing data to study cell–cell communication.
📣 Listen up: you only have a few more days to apply for #EMBOSpatialOmics!
Would you like to get a comprehensive introduction to the various methods of spatial-omics and in particular those of multiplex immunofluorescence and spatial transcriptomics?
Then apply for this hands-on EMBO Practical Course by 10 March ✍️
🌍 EMBL Heidelberg
📅 15 – 20 June 2025
💻 https://s.embl.org/iso25-01-ma
#spatialtranscriptomics #microscopy #imageanalysis #spatialbiology #spatialomics
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