The objective of this study is to describe the prevalence of inflammatory cardiopulmonary findings in a prospective cohort of long coronavirus disease (LC) patients. Methods: Subjects with a history of coronavirus disease 2019 infection, persistent cardiopulmonary symptoms 9–12 mo after initial infection, and a clinical assessment compatible with LC underwent cardiopulmonary 18F-FDG PET/MRI, dual-energy CT (DECT) of the lungs, and plasma protein analysis (subgroup). A control group that included subjects with a history of acute severe acute respiratory syndrome coronavirus 2 infection but without cardiopulmonary symptoms at recruitment was also characterized. Results: Ninety-eight patients (median age, 48.5 y; 47% men) were enrolled. The most common LC symptom was shortness of breath (80%), and 27% of participants were hospitalized. Of the subjects, 90% presented abnormalities in DECT, with 67% and 59% of participants demonstrating pulmonary infiltrates and abnormal perfusion, respectively. PET/MRI was abnormal for 57% of subjects: 24% showed cardiac involvement suggestive of myocarditis, 22% presented uptake reminiscent of pericarditis, 11% showed periannular uptake, and 30% showed vascular uptake (aortic or pulmonary). There was no myocardial, pericardial, periannular, or pulmonary uptake on the PET/MRI scans of the control group ( n = 9). Analysis of plasma protein concentrations showed significant differences between the LC and the control groups. Lastly, the plasma protein profile was significantly different among LC patients with abnormal and normal PET/MRI. Conclusion: In LC subjects evaluated up to a year after coronavirus disease 2019 infection, our results indicate a high prevalence of abnormalities on PET/MRI and DECT, as well as significant differences in the peripheral biomarker profile, which might warrant further monitoring to exclude the development of complications such as pulmonary hypertension and valvular disease.
Games uniquely incorporate emotional and social factors that influence how we take in information — making them surprisingly useful communication tools in a world in denial about the ongoing threats of COVID-19 and Long COVID. Whether through the cathartic storytelling in indie designers’ interactive theater projects or learning opportunities woven into popular video games, playing games can help people make informed decisions amid the Long COVID crisis.
From "Kids keep getting sicker as evidence for COVID immune damage builds ", by Julia Doubleday:
"The data doesn’t lie, and a Bloomberg News analysis showed that:"Back in January, Canada's national vaccine advisory body set the stage for another round of spring vaccinations. In a statement, the National Advisory Committee on Immunization (NACI) stated that starting in spring 2024, individuals at an increased risk of severe COVID may get an extra dose of the latest XBB.1.5-based vaccines, which better protect against circulating virus variants.
That means:
-Adults aged 65 and up.
-Adult residents of long-term care homes and other congregate living settings for seniors.
-Anyone six months of age or older who is moderately to severely immunocompromised.”
https://www.cbc.ca/news/health/spring-covid-vaccine-1.7156121
"The documents, obtained through an access to information request, consist of dozens of pages of communications between officials at Alberta Health, the government ministry, and Alberta Health Services, the provincial health authority. They show that, in addition to ordering AHS to remove references to specific vaccines, the government instructed the health authority to limit information on vaccine benefits and efficacy.”
Alberta's COVID death toll up by 17 since last week, with 190 more hospitalizations:
https://www.cbc.ca/news/canada/calgary/alberta-covid-weekly-data-summary-dec-16-2023-1.7067271
#alberta #ableg #canada #covid #covid19