Had a wonderful first trip to Mexico🇲🇽 last week to speak about laryngopharyngeal reflux disease (LPRD🔥) at the NeuroGastro Congress. Thank you to my friends/colleagues from La Asociación Mexicana de Neurogastroenterología y Motilidad (AMNM) for the invitation and warm hospitality❤️ Look forward to more exciting collaborations in the future!
#BWHMotility #GERD #LPR #esophagus #gimotility #NeuroGastroenterology
Honored to visit and speak at NYU GI Grand Round on #GERD & esophageal function testing in chronic lung disease. Thank you to my friends & colleagues at the NYU Center for Edophageal Health and the GI Division for the invitation & hospitality!
Grateful for the opportunity to discuss our work in extraesophageal GERD at Mayo Clinic GI Grand Round in Arizona🌵!
Had a wonderful day meeting colleagues, discussing cases with fellows & seeing my friends. Thank you to Dr. Marcelo Vela and the amazing #MayoEsophageal team for inviting & hosting me. Look forward to more collaborations in the future!
Our new study in this issue of #CTGJournal analyzed gene transcript expressions on mucosal biopsies of patients with eosinophilic esophagitis (#EoE)
🧬Transcript profiles similar between PPI-responsive (PPI-R) & non-responsive (PPI-NR) EoE
🧬PPI-R EoE shares Th2 inflammatory signature of PPI-NR EoE
String and a custom panel of EoE-specific genes. The top upregulated and downregulated genes with ≥2-fold difference in expression and statistically significant (P < 0.05) were identified. RESULTS: Nearly all the top upregulated (17 of 20) and downregulated (5 of 5) genes in EoE, compared with healthy controls, were shared between the PPI-R and PPI-NR groups. DISCUSSION: Esophageal mucosal transcript expressions are remarkably similar in PPI-R EoE and PPI-NR EoE compared with healthy controls....
Walter Chan, MD, MPH