@alice May I ask what the three #vaccines were?

I'm a pharmacist, and I've been a radical PRO-vaxer literally since childhood. Louis Pasteur was one of my childhood heroes. So when I got my first dose of #Shingrix a few years ago, and this brutal adjuvanted vaccine made my whole right arm turn red and warm from the injection site in the deltoid all the way down to my wrist, it didn't bother me in the least. Quite the contrary. I thought, "Good! This is exactly the red alert my immune system needs."

I knew that Shingrix was more effective than the old #Zostavax live vaccine against #shingles, which I had also gotten. Not long ago it had been thought impossible for a recombinant vaccine like Shingrix to be more effective than the best available live vaccine, but the rules are rapidly being rewritten by modern #adjuvant technology.

What I was NOT prepared for was the flood of good news about Shingrix from observational research — the exact opposite of #antivaxer paranoid fantasies. I'll be the first to admit that the picture isn't clear yet — science works by theory based on the accumulated totality of observational and experimental evidence, not by overconfident extrapolation from individual studies. But it’s looking as though Shingrix has astonishing benefits above and beyond its basic purpose of preventing shingles. And the benefits may even extend to other modern adjuvanted vaccines.

Vaccination against shingles was expected to provide some protection against #dementia, simply because herpes #zoster, the virus that causes shingles, is a known risk factor for dementia. But observational studies showed statistically that the reduction in new-onset dementia began right away — too quickly for it to be purely the result of suppression of shingles attacks, which are infrequent. And now evidence is starting to appear that suggests that Shingrix may have a general anti-aging effect through some kind of "tuning" of the immune system — as may at least some other adjuvanted vaccines.

How ironic. This is the kind of very general benefit that homeopaths and such tend to claim, dubiously, for their panaceas — and now it looks as though modern biomedical high technology has achieved it for real, without even trying.

Think about that as your immune system on red alert is making you, very temporarily, feel miserable.

#alt4u

Slides # 2, 5, 7, 9, and 10 from a presentation entitled #Data in Support of #Novavax XBB.1.5 #Vaccine. Link at the end of the post.

It presents the recombinant protein particle plus matrix-M #adjuvant. There is data showing the neutralizing responses of serum from vaccinated macaques against #pseudoviruses made with different variant's spikes.

https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2023-09-12/09-COVID-Dubovsky-508.pdf

@enirenberg

I’m really shite at explaining things. I shovel info into my brain, note what repeated actions practically I have to take or what to avoid & leave the rest. Explaining is not my gift which is why I love others whose gift it is🖤

His response: (which came really quickly I might add🥰😍)

“No studies have been performed to measure nanoparticle-spike persistence in local or distal tissues”

And no studies have tested whether there’s a blue teapot orbiting Jupiter either (scientist snark) Point is that sure, this could be an issue. Sure, the nanos could also infest your brain, or it could this or that, but that doesn’t invalidate anything. This is FUD, (fear, uncertainty & doubt) - not invalid, but not a valid issue

“ ◦#Novavax expects a low potential for serious unwanted effects and toxicities in neonates, infants, and children” (they don’t know)
◦ “Novavax expects a low potential for serious unwanted effects and toxicities in pregnant women and fetuses” (they don’t know)
◦ “Novavax does not believe there are other special populations which would be more susceptible for serious unwanted effects and toxicities” (they don’t know)”

This is just dumb - who is this guy? Probably a MD, they think they understand science. Science doesn’t find Truth, it discovers truth. It will never be all encompassing. Short answer, we always will know less than can be known, so saying “they don’t know” is just asinine, of course they don’t! They can’t.

Addendum - studies cherry pick, you have to there’s never enough time or money. They studied the big issues, doubtful these are anything which is why they weren’t studied, and for darn sure getting COVID is worse (dumbass)

biodistribution of Novavax nanoparticle-spike has never been done and company “assumes” that it “mostly” stays in local lymph nodes because it should behave like a “conventional protein antigen” (it’s NOT, it’s a nanoparticle)

This looks like scare mongering, he doesn’t say anything but the word NANOPARTICLE is supposed to inspire fear, or something. A null statement.

OK

ALSO contains a saponin-based #MatrixM #adjuvant (40nm #nanoparticle, remarkably stable, held together by saponin-cholesterol interactions” (in rodents causes decreased body weight and red cell mass) – “may contribute to immunotoxicity”

This also is stupid - ask **** about how many times she’s heard **** or I say ANYTHING for certain - we don’t. We qualify everything. Built into techy types, we know nothing is known for 100% certainty - if you want that go join a religion

Yeah that’s probably enough too much to bother with, another technique FUD masters use is loooong, highly detailed posts that look smart and scientific, but it’s part of the advertising. Real scientists cut it short - that’s why there’s a précis/summary at the top. Get the idea in a paragraph and read the rest if you care

-End

Also his response to my Halloween wishes cracked me up🎃

Alas, must continue on that ball gown pattern I started yesterday (wrap apron dress but put anything poufy underneath instant ball gown) hence goblin trick 2 for tomorrow. These goblins & ghouls are so draining