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HAPPY STRAIGHT EDGE DAY
From here on, as much as possible..
It's about self-love and self-care.
I've even slowed down doing the things I love.. Just becoz it doesn't feel right at the moment.
Maybe I just need a break.. From everything.
Maybe breaking the cycle is a good thing once in a while
Staying positive in a cruel world is not easy.. But keep going.
Things happen for a reason. Always.
#StraightEdge #SXE
#17October #Xup
#EdgeDay #PoisonFree
#DrugFree #12XU
Repeater by Water Damage, released on 12XU in 2021
There is something really special about music based on drones. Whether it's the vocals of Pandit Pran Nath, the ARP 2500 of Eliane Radigue, or the nearly-blown amps of Sunn O))), by changing the listeners's focus on details to one that favors flow, drones are uniquely capable of transporting our brains far far away. The debut LP, 'Repeater', by this loudly droning Austin septet is a goddamn splendid example of how the process works. Using the motto, “Maximal Repetition Minimal Deviation,” Water Damage create glowing fields of post-rock lava that pretty much suck you right in and boil you alive.
Water Damage, while technically a septet, actually operate in various configurations, with the proviso there should always be two drummers and two bass players on hand...
https://waterdamage12xu.bandcamp.com/album/repeater
https://www.youtube.com/watch?v=p8u8zttK66k&list=RDp8u8zttK66k&start_radio=1
L'Australie un jour, l'Australie toujours !
Through Today, 2ème album du duo Chimers et ça claque toujours autant.
http://www.perteetfracas.org/zine/kros2025/kros_c/chimers_through_today.htm
New 🐌 paper alert! We showed that snails with v. few mtDNA copies per nuclear genome (<10) have a v. high rate of heteroplasmy; heteroplasmy is inherited through the germline, albeit with selection against synonymous mutations. We also found that some mtDNA genomes have tRNAs that are repeated up to 24 times! https://doi.org/10.1186/s12864-024-10505-w
#PaperThemeTune "12XU" by Wire https://youtu.be/jOjCSLMZPok (mainly because I just rediscovered it 😄) #snails #mtDNA #genomics #heteroplasmy #cepaea #wgs #12XU #wire
Molluscan mitochondrial genomes are unusual because they show wide variation in size, radical genome rearrangements and frequently show high variation (> 10%) within species. As progress in understanding this variation has been limited, we used whole genome sequencing of a six-generation matriline of the terrestrial snail Cepaea nemoralis, as well as whole genome sequences from wild-collected C. nemoralis, the sister species C. hortensis, and multiple other snail species to explore the origins of mitochondrial DNA (mtDNA) variation. The main finding is that a high rate of SNP heteroplasmy in somatic tissue was negatively correlated with mtDNA copy number in both Cepaea species. In individuals with under ten mtDNA copies per nuclear genome, more than 10% of all positions were heteroplasmic, with evidence for transmission of this heteroplasmy through the germline. Further analyses showed evidence for purifying selection acting on non-synonymous mutations, even at low frequency of the rare allele, especially in cytochrome oxidase subunit 1 and cytochrome b. The mtDNA of some individuals of Cepaea nemoralis contained a length heteroplasmy, including up to 12 direct repeat copies of tRNA-Val, with 24 copies in another snail, Candidula rugosiuscula, and repeats of tRNA-Thr in C. hortensis. These repeats likely arise due to error prone replication but are not correlated with mitochondrial copy number in C. nemoralis. Overall, the findings provide key insights into mechanisms of replication, mutation and evolution in molluscan mtDNA, and so will inform wider studies on the biology and evolution of mtDNA across animal phyla.
RUROUNIxZOMBIE
Andi Chorley
Perte & Fracas
Jenkelly
Moshtrocity Radioshow
Angus Davison
groschi
