Sarah Clatterbuck Soper

@sclatter
36 Followers
159 Following
10 Posts
Aficionado of nucleic acids and the proteins that love them.
@jwz in my nerd girl dorm circa 1989 The Lost Boys was an absolute obsession, complete with a townie boy who cosplayed as David and made the rounds of the girls. (Not me, I wasn’t nearly cool enough) Recently became aware I can still ID the opening credits by ear within about three seconds. Favorite? No. But deeply ingrained.
@violetblue Thank you for this important report in telomere biology. Since this is my scientific specialty it was of particular interest.
Happy #caturday
@[email protected] I always used to run hot but after losing weight I feel cold all the time! I have learned to love layering. Hoping a squishy, comfortably warm sweater is in your future.
@cbroome I plan to valiantly eat as much ramen as possible to support their revitalization of Greenmount.
@cbroome As a Better Waverly resident I am extremely excited about this!
@albertcardona @peiferlabunc @martinho_lab Even in the US with functional (and even purpose built supplementary!) AC my PhD lab gave up on RNA Native Gels in summer. I kind of suspected it was less about heat than humidity—the rigs were cold and water condensed on the gels as they ran.

Hey everyone, Happy Holidays! I come bearing the gift of our last preprint of 2022.

https://www.biorxiv.org/content/10.1101/2022.12.26.521943v1

Will probably run a legit "Toot-orial" in the New Year when people are back, but briefly: We have long been interested in how the genome is packaged in sperm, both as a cool chromatin state and also because several labs have reported that mutations that affect histone modifications in the testis have intergenerational effects. 1/n

@cellosaurus U2OS is easy to grow and gorgeous to image but it seems like people don’t always take full account of its ALT status when using it for nuclear experiments. We don’t completely understand all the things implied by being ATRX null. DNA repair, chromatin state and nuclear foci are all going to be “weird” relative to a TERT cell.
@sbarolo this is like trying to pick a favorite child. Ultimately chose Mononoke because it was the first I saw and blew my mind at the time.