Mastodawn

Maik Pietzner May 4, 2023

RT @aidanbutty
Congratulations again @Julia_Czs on a great thesis and viva, and congrats to @pietznerm, Claudia, Nick and the rest of the team @MRC_Epid for supporting such great science! 😃🥳🙌🎉 https://twitter.com/ProfJohnATodd/status/1654089569350955008

John Andrew Todd on Twitter

“Brilliant PhD viva by Julia Sanchez- fantastic science. Fellow examiner Adam Butterworth and I were deeply impressed. Congrats, Julia!!!”

Twitter

Maik Pietzner May 3, 2023

😂😂😂
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RT @DanielJDrucker
When will GLP-1-based therapies for #obesity #weightloss be tossed aside for robust #microbiota based solutions? "Our growing knowledge of microbial contributions to energy metabolism highlights new opportunities for weight management" @NatureRevMicro https://www.nature.com/articles/s41579-023-00888-0
https://twitter.com/DanielJDrucker/status/1653809810121404424

Roles of the gut microbiome in weight management - Nature Reviews Microbiology

In this Review, Carmody and Bisanz examine the role of the gut microbiome in energy metabolism, the two-way relationship between the gut microbiome and weight management strategies and opportunities and challenges in the development of microbiome-directed therapies targeting energy balance.

Nature

Maik Pietzner Apr 29, 2023

RT @Dr__Guess
Kind of wild to spend 3 days at a conference on *cough* actual diabetes & see this rubbish again from @Join_ZOE

Let me repeat for nutrition companies that can’t be bothered to get a diabetologist on staff:

IF YOUR GLUCOSE GOES UP TO 7MMOL/L AFTER A MEAL NO THIS ISN’T DIABETES

Maik Pietzner Apr 28, 2023

RT @mitchiela
LDlink update: Use of #LDlink has substantially expanded and at times exceeded our ability to keep up with demand. I am beyond thrilled to announce implementation of a #serverless architecture for improved performance, reliability, and scalability.
https://ldlink.nci.nih.gov/

LDlink | An Interactive Web Tool for Exploring Linkage Disequilibrium in Population Groups

LDlink is a suite of web-based applications designed to easily and efficiently interrogate linkage disequilibrium in population groups.

Maik Pietzner Apr 26, 2023

Great overview of the new #proteomics data in @uk_biobank by @chrisdwhelan @ksuhre Ben Sun, Naomi Allen and others

Thanks for name dropping @chrisdwhelan 😉

paper https://www.nature.com/articles/s41467-021-27164-0

also @OlinkProteomics 3k pQTLs here https://www.nature.com/articles/s42255-023-00753-7 @KopruluMine
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RT @OlinkProteomics
Join representatives from @uk_biobank, Janssen, Biogen, Olink, Weill Cornell Medicine - Qatar &…
https://twitter.com/OlinkProteomics/status/1649392123937005571

Synergistic insights into human health from aptamer- and antibody-based proteomic profiling - Nature Communications

Broad-capture affinity-based proteomic technologies inform how the readout of our genes affects human health. Here, the authors integrate aptamer- and antibody-based profiling to understand the mechanisms underlying gene-protein-disease associations.

Nature

Maik Pietzner Apr 26, 2023

RT @CPMOxford
We've started to upload the recordings of last week's Polygenic Risk Scores event. Watch thought-provoking talks by @annekeluc, @amit_sud, Aroon Hingorani and @cathrynlewis.

https://shorturl.at/ijHKZ

Polygenic Risk Scores

Opportunities & challenges for polygenic risk scores in healthcare This event took place on 18 April 2023 at St Anne's College, Oxford

YouTube

Maik Pietzner Apr 25, 2023

RT @NatMetabolism
RESEARCH | @KopruluMine @pietznerm et al. (@MRC_Epid @berlinnovation @QMUL):

The authors integrate antibody-based proteomic data with genomics to link protein-encoding genes to human metabolic disease.

#proteomics #genomics

https://www.nature.com/articles/s42255-023-00753-7

Proteogenomic links to human metabolic diseases - Nature Metabolism

Koprulu et al. integrate antibody-based proteomic data with genomics to link protein-encoding genes to human metabolic disease.

Nature

Maik Pietzner Apr 24, 2023

I am delighted to welcome everyone to my inaugural lecture on using #Genetics #Proteomics and #EHRs for #drug discovery

At my new (partial) home @QMUL at the newly founded Precision Healthcare University Research Institute

*16th May - 4pm*

Maik Pietzner Inaugural lecture

We welcome you to the inaugural lecture of Professor Maik Pietzner followed by a reception.

Eventbrite

Maik Pietzner Apr 20, 2023

RT @merenbey
Now this is out, I would like to tell you what I learned from this study about the human gut microbiome (and its place in noncommunicable diseases of complex etiology, such as Crohn's and ulcerative colitis). https://twitter.com/awatsontxt/status/1648420614737371136

Andrea Watson on Twitter

“Delighted to announce the publication of this work from my PhD! We show that metabolically independent microbes associated with human gut “dysbiosis” may not in fact be causal of disease, but instead selected for under stressful conditions. (1/4) https://t.co/fPa4tq9ZGi”

Twitter

Maik Pietzner Apr 17, 2023

RT @SashaGusevPosts
A 🧵 on some of my intuitions/priors about the genetics of complex and molecular traits in humans (i.e. what I think of as typical), largely motivated by GWAS/QTL studies over the past decade [citing papers with nice figures where possible]