Now out in @[email protected] :
"#Neuroforecasting reveals generalizable components of choice" (link below)!

Led by the intrepid Alex Genevsky , we examined how deep brain activity (in the Nucleus Accumbens or #NAcc ) can forecast choices out of sample in much larger groups (e.g., in #crowdfunding and #videoviewing markets).

We found that while behavioral forecasts depended on demographic match, neural forecasts (from the NAcc) did not, potentially supporting inferences from smaller samples. So, beyond considering #representativeness of a sample, researchers might also benefit from considering representativeness of different choice components.

Thanks to the Wu Tsai Neurosciences Institute #Neurochoice Initiative for support, to the reviewers for constructive suggestions, and to #PNASNexus for a smooth publishing experience!

https://academic.oup.com/pnasnexus/article/4/2/pgaf029/8016018

Congratulations to Laramie Duncan and #Stanford collaborators on publishing "Mapping the cellular etiology of schizophrenia and complex brain phenotypes" in @natureneuro !

Combining brain-wide genetics and transcriptomics analyses implicated different cell types in #schizophrenia (e.g., retrosplenial excitatory and striatal MSN) versus other disorders (e.g., D2 MSN in alcohol consumption). Excited to explore and learn more with this promising new approach...

https://www.nature.com/articles/s41593-024-01834-w.epdf

Floyd Bloom, who died on 8 January at age 88, authored the classic textbook “The Biochemical Basis of Neuropharmacology” and expanded our understanding of the roles of neurotransmitters in the brain.

By Sydney Wyatt

https://www.thetransmitter.org/neuropharmacology/remembering-the-life-of-floyd-bloom/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20250124-obit-floyd-bloom

Scientific #discovery involves making mistakes, but these are often omitted from official reports. In this preprint, I recount a #mistake which led to the discovery that #rats were making ultrasonic #vocalizations while playing. Scientific serendipity is worth celebrating! (thanks to Markus Wöhr for encouragement to submit the tale for a special issue on ultrasonic vocalizations).

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5108903

Engaging backstory on the evolution of meta-analyses and large scale collaborations ( i.e., #ABCD ) by Angela Laird as interviewed by Peter Bandettini on the #neurosalience podcast ( #FMRI , #neuroscience , #ohbm ):

https://www.youtube.com/watch?v=d7Jh7JFGf1Q

Check out this very clear and insightful podcast with my favourite #DecisionMaking #Neuroscientist @adredish ! A lot of food for thought about the decisions we make, the habitual ones, the deliberative ones, the instinctive ones, and what happens when these systems are in conflict:

https://neuromatch.social/@adredish/113624315622020263

75+ Nobel Prize winners have signed a letter urging senators not to confirm Robert F. Kennedy Jr. as head of the Department of Health and Human Services.

The letter marks the first time in recent memory that Nobel laureates have banded together against a Cabinet choice.

https://www.nytimes.com/2024/12/09/health/kennedy-hhs-nobel-laureates.html