A wave of new papers discuss the merits and limitations of lesion network mapping.

By Angie Voyles Askham

https://www.thetransmitter.org/brain-imaging/overdue-debate-unfurls-over-neuroimaging-method/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260417-news-brain-imaging-debate-unfurls-over-neuroimaging-method

Visit our courses calendar, where we highlight the top neuroscience courses that should be on your radar. You can filter your search by topic.

https://www.thetransmitter.org/courses/?utm_source=x&utm_medium=org-social&utm_campaign=20260416-courses-cal-rp

Nearly 400 compounds displayed significant effects on at least two behavioral parameters in zebrafish with SCN2A or DYRK1A variants, according to a new study.

By Charles Q. Choi

https://www.thetransmitter.org/animal-models/nearly-400-compounds-affect-behaviors-tied-to-autism-linked-genes-in-zebrafish/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260416-news-sp-400-compounds-affect-behaviors-tied-toautism-linked-genes-zebrafish

Neuroscientists across the United States shared with The Transmitter what they hope the new director of the National Institute of Neurological Disorders and Stroke prioritizes during their tenure.

By Helena Kudiabor

https://www.thetransmitter.org/policy/what-neuroscientists-want-from-a-new-ninds-director/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260415-news-policy-what-neuroscientists-want-from-a-new-NINDS-director

When it comes to blood flow in the brain, not all neurons are created equal. Rather, only a subset of neurons may be driving vascular changes, a new study finds.

By Claudia López Lloreda

https://www.thetransmitter.org/neurovascular-system/arousal-neurons-activity-explains-brains-blood-flow-dynamics-in-mice/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260415-news-embargo-neurovascular-system-brain-blood-flow-dynamics-mice

In our latest edition of “This paper changed my life,” Erin Calipari shares how a 1960s paper taught her to think deeply about factors that influence how behavior is generated and maintained.

https://www.thetransmitter.org/this-paper-changed-my-life/this-paper-changed-my-life-erin-calipari-ponders-the-nuances-of-rewarding-and-aversive-stimuli/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260414-tpcml-erin-calipari

These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity, writes Juan Alvaro Gallego. But will we be able to understand them?

https://www.thetransmitter.org/neuroai/why-neural-foundation-models-work-and-what-they-might-and-might-not-teach-us-about-the-brain/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260413-perspectives-neuroai-why-neural-foundation-models-work

A single equation governs the brain’s flexible behavior and predicts how well brains and artificial networks can generalize across tasks.

By Natalia Mesa

https://www.thetransmitter.org/systems-neuroscience/error-equation-predicts-brains-ability-to-generalize/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260410-news-error-equation-predicts-brains-ability-to-generalize

Explore “Brainstorming,” @thetransmitter's new LinkedIn newsletter that looks at how neuroscientists are solving research challenges.

https://www.linkedin.com/pulse/nontraditional-model-organism-renaissance-thetransmitter-svlee/

“Recognizing the scope and impact of heterogeneity in basic neuroscience is essential if we want to understand complex conditions and the brain in health and disease,” write Linda Douw, Klaus Eyer and Lara Keuck.

https://www.thetransmitter.org/science-and-society/embrace-complexity-to-improve-the-translatability-of-basic-neuroscience/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20260409-perspectives-science-society-embrace-complexity-improve-translatability-basic-neuro