Mérel et al. use WGS data from 77 Drosophila species, finding that genome size and TE content correlate with relaxed selection, especially in GC-poor genes.

🔗 doi.org/10.1093/molbev/msaf111

#evobio #molbio

In a new Review article, Hu et al. propose "Conservation Evolutionary Biology" as a new subdiscipline of conservation biology that integrates evolutionary history and ecosystem dynamics to guide biodiversity conservation.

🔗 doi.org/10.1093/molbev/msaf122

#evobio #molbio #conservation

Is MEGA-GPT heralding a new age of accessibility in bioinformatics with dedicated chatbots to help guide users? Read more in MBE's new Highlight: "MEGA into the New Generation of Computational Genetics"

🔗 doi.org/10.1093/molbev/msaf108

#evobio #molbio #bioinformatics #AI

Using an experimental evolution platform @farhanrc.bsky.social & @chemtips.bsky.social show that tripartite antibiotic loops - sequential regimens involving three antibiotics - can resensitize bacteria to the 1st drug as multidrug resistance evolves

🔗 doi.org/10.1093/molbev/msaf115

#evobio #molbio

John Allard‬ & Sudhir Kumar introduce MEGA-GPT, an AI assistant that aims to improve the usability of the feature-heavy MEGA software by guiding users through MEGA's options via natural language queries.

🔗 https://doi.org/10.1093/molbev/msaf101

#evobio #molbio #bioinformatics

The June cover of Molecular Biology and Evolution features the work of de Bakker et al., who studied the developmental genetics of amniote limb phenotypes.

🔗 doi.org/10.1093/molbev/msaf113

📷 Gerda Lamers

#evobio #molbio #evodevo

Policarpo et al. use phylogenetic and synteny data to identify 19 teleost-to-teleost horizontal gene transfers in 11 orders, involving genes linked to immunity or pore formation; this suggests eukaryote-to-eukaryote HGT has shaped teleost evolution.

🔗 doi.org/10.1093/molbev/msaf107

#evolbio #molbio #fish

Okuno et al. assemble male genomes for three spiny rat species, tracing Y chromosome loss and gene translocation. Authors show that segmental duplications and rearrangements enabled preservation of Y-linked genes on the X.

🔗 doi.org/10.1093/molbev/msaf102

#molbio #evobio #sexchromosomes

Tuffaha, Wahl et al. analyzed tumors from 20 tissues to show that nonhypermutated tumors reverse germline mutation biases, facilitating adaptation without elevated mutation rates.

🔗 doi.org/10.1093/molbev/msaf105

MBE is a leading journal in genetics and evolutionary biology, but this is not the sole reason for submitting your research to us.

Check these important reasons for choosing MBE and our sister journal @GenomeBiolEvol to publish your next article: https://academic.oup.com/mbe/pages/why-publish