Markku Hakala

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120 Following
35 Posts
Postdoc researcher at University of Geneva studying membrane remodelling machineries with in vitro tools, fluorescent microscope and electron microscope. Interested also about cytoskeleton, membrane trafficking and organelle dynamics. Also @mhakala.bsky.social
Vinculin Antagonizes Branched Actin in Controlling Membrane Protrusion, Cell Migration and Cell Cycle Progression https://www.biorxiv.org/content/10.1101/2023.10.09.561480v1?med=mas

Postdoc - Membrane Protein Transport into Cilia

University of Oxford

Exciting opportunity to join the Roberts group @Dunn_School to study how #membraneproteins are transported into #cilia using #cryoEM

See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-oxford-27778-postdoc-membrane-protein-transport-into-cilia/?feed_id=59857

#ScienceJobs #hiring #res...
https://jobrxiv.org/job/university-of-oxford-27778-postdoc-membrane-protein-transport-into-cilia/?feed_id=59857

Postdoc - Membrane Protein Transport into Cilia

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobRxiv

I was about to write my #review for a 30-page equation-rich revision in #JMPS edited by #elsevier. It was "overdue" by 2 work days (although, well, is Elsevier my employer to give me assignments?)

So I looked up the emails to find the link to their review thingy.

Surprise: I find in an unopened email dated 11 Sep, which I had thought was a reminder, the note:

"Thank you for reviewing the above referenced #manuscript. With your help, I have reached an accept decision"

1/3
@academicchatter

Does anyone have any experience about publishing in JoVE (Journal of Visualized Experiments)? Is it worth it? Are people reading? How much work it requires?

📣 📣 📣 The shock of my day:

Over the last few days, I measured the power consumption of our -80°C freezers:

~13 kWh per day (each)

 So, one freezer consumes much more electricity per year than my family and me... 🙁

Now, we finally put them from -80°C to -70°C.
( & we need to minimize the number of samples we store)

An update will follow.

#GreenLab #Sustainability #KlimaSchutz #Research #Science #Klimawandel #climatechange #Nachhaltigkeit
@UniKoeln @CECAD
@s4f_koeln_bonn

Please recommend me reviews and why not also research articles related to membrane mikrodomains and protein assemblies, eg. actin, clathrin, caveolae etc. Need some holiday reading! 😂
RT @felixmendu
In a couple of weeks (March 30), we will have our new session of the #membranetrafficking online talks! This time we moved to Asia-Pacific (so the time will be different!), and we are very happy to be hosting @brettcollins100 from @IMBatUQ, and Lei Lu from @NTUsg
Guys need bit of help! I need measure BAR protein insertion into the #membrane bilayer. No need for exact depth calculations but indication if WT protein inserts and mutant doesn’t. I’ve used DPH anisotrophy assays to study this but are there other options that don’t need months of optimization? #deadline
Interesting and annoying observation: my protein-of-interest sticks to the glass heavily. Passivation of glass with BSA or Casein doesn’t help too much. The worst thing is that when this protein is bound on GUV membrane it drags vesicles on glass too and makes them stick and finally explode on glass. Any suggestions for better passivation method? Something quick and easy please :) I’m considering PEG-silane approach
I’m hiring a post-doc to work on modeling mechanics in bioengineered cells/tissues using particle dynamics @[email protected] near Milan, Italy. Strong coding skills and a background in computational biology, physics, mathematics or software engineering required. DM me for info.