Eduardo Rocha

549 Followers
159 Following
72 Posts
Researcher on microbial evolutionary genomics @CNRS and @InstitutPasteur

Great work showing thousands of novel phage satellites across hundreds of Bacterial spp by @doctor_jams @epcrocha
@jrpenades and @AlfredFillol
Includes software to find them.

https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad123/7068371?login=false

Identification and characterization of thousands of bacteriophage satellites across bacteria

Abstract. Bacteriophage–bacteria interactions are affected by phage satellites, elements that exploit phages for transfer between bacteria. Satellites can encod

OUP Academic

RT @EvolvedBiofilm
Horizontal Gene Transfer, Fitness Costs and Mobility shape the spread of antibiotic resistance genes into experimental populations of Acinetobacter baylyi

@molbioevol from @MikeJayMcD

https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msad028/7036842

Horizontal Gene Transfer, Fitness Costs and Mobility shape the spread of antibiotic resistance genes into experimental populations of Acinetobacter baylyi

Abstract. Horizontal Gene Transfer (HGT) is important for microbial evolution, but how evolutionary forces shape the frequencies of horizontally transferred gen

OUP Academic
RT @IsbergRalph
Cooperative virulence via the collective action of secreted pathogen effectors | Nature Microbiology https://www.nature.com/articles/s41564-023-01328-8
Cooperative virulence via the collective action of secreted pathogen effectors - Nature Microbiology

Virulence can be endowed through the collective action of effectors.

Nature
Lucy Weinert & I are co-hosting a symposium on experimental evolution in non model organisms for SMBE: https://www.smbe2023.org/symposia
If you work in this area, please consider submitting an abstract. The due date is March 15. See you in Italy!
Symposia | Smbe2023

Smbe
RT @alison_mudditt
Happy birthday to @PLOSBiology, our first journal! So much has been achieved for #OpenAccess and #OpenScience in those 3 decades. I'm proud of the journal's role in this and their ambition to continue the transformation of research communication 🎂🍾
Competence in #Streptococcus controls genetic transformation, biofilm formation & virulence. @JWVeening &co show that it's also crucial for host #adherence, involving the fratricin CbpD, which exposes #virulence factors to the cell surface #PLOSBiology https://plos.io/3DtTwmJ
Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence

Competence development in the human pathogen Streptococcus pneumoniae controls several features such as genetic transformation, biofilm formation and virulence. This study shows that competence activation is crucial for optimal host adherence, via a mechanism dependent on the fratricin CbpD, which exposes virulence factors to the cell surface.

RT @FrunzkeLab
Very much looking forward to our International Symposium on "New concepts in prokaryotic virus-host interaction", organized in the frame of @SPP2330; October 2-4 in Berlin!!
Further information will follow soon: http://www.spp2330.de
SPP 2330 – New Concepts in Prokaryotic Virus-host Interactions

What Lies Beneath? Taking the Plunge into the Murky Waters of Phage Biology

@mSystemsJ MiniReview by @MirjamZuend et al from @KatrineWhiteson

https://journals.asm.org/doi/10.1128/msystems.00807-22

Very glad to see this work published in @[email protected] today! 🥳

Thanks to all the team, and to our constructive reviewers during this process!

https://www.nature.com/articles/s41559-022-01956-z

RT @[email protected]

New preprint!
We reconstructed the genomes of 624 (!) ancestral vertebrates, plants, fungi and protists!
And they’re all available - you’re welcome! :D

A thread 🧵 on a project that has been long in the making...! (1/n)

https://www.biorxiv.org/content/10.1101/2022.02.17.480882v1

🐦🔗: https://twitter.com/CamLBerthelot/status/1495767738496823308

Reconstruction of hundreds of reference ancestral genomes across the eukaryotic kingdom - Nature Ecology & Evolution

Using an algorithm for ancestral genome reconstruction, the authors present 624 ancestral genomes for vertebrates, plants, fungi, metazoans and protists and reconstruct the chromosomal rearrangement history of all major vertebrate clades.

Nature
RT @GillesvanWezel
I am very pleased to announce that Akos Kovacs @EvolvedBiofilm will join @LeidenBiology as Professor of Microbiome Ecology, as of 1 July 2023. He is a world-leading expert on biofilms and will complement our expertise in host-microbe interactions. Welcome to @LeidenScience Akos!