Cass Irons

@drcassirons
3 Followers
15 Following
69 Posts
#introduction
I'm Cass. Former pharma, now a wellness skeptic with a chemistry background and a low tolerance for nonsense.
What I do here:
– Break down the studies that wellness influencers cite (and what they actually say)
– Call out predatory marketing in the supplement industry
– Push back on bad takes from both wellness AND mainstream medicine
– Update my views in public when new evidence comes in
What I don't do:
– Give medical advice
– Pretend I have all the answers
– Punch down at people
“Clinically studied ingredients” is a gorgeous little loophole. It can mean one ingredient was tested somewhere, at some dose, in some population, while the product in your cart is a confetti cannon of extras. Product-level claims need product-level evidence. #Science #Supplements
“Hormone balancing” sounds medical until the paperwork starts. Which hormone? Measured how? In whom? Compared with what? If the endpoint is “felt more aligned,” that is not endocrinology. That is a mood board with a checkout button. #Health #Science #Supplements

Biohacking has become a beautiful word for putting basic physiology in a hoodie and charging a subscription fee.

If the endpoint is “feel optimized” and the checkout has three upsells, I am begging everyone to locate the methods section. #Science #Health

Source: Mah and Pitre. BMC Complementary Medicine and Therapies 21:125, 2021. Meta-analysis of 3 RCTs, 151 older adults with insomnia symptoms. Modest reduction in sleep onset latency (~17 min) and increase in total sleep time (~16 min). Younger populations were not included; the effect is not established outside the studied age group. DOI 10.1186/s12906-021-03297-z.

“Clinically studied ingredients” is doing Olympic-level evasive work. Which ingredient, what endpoint, whose trial, and did the product actually match the studied dose?

The supplement aisle found a lab coat and got theatrical. #Supplements #Science

'Supports cellular health' is often what marketing says when outcomes would require evidence. Cells: famously present in most health claims.

#Supplements #Science

Testimonials are not trials. Before-after photos are not endpoints. And “my clients love it” is not a methods section, no matter how tastefully beige the sales page is. #Science #Health

Most of the world's oldest people are dead.

Or something like that.

A review of the book *Morbid* that debunks longevity 'science'.

https://www.sciencenews.org/article/morbid-book-debunks-antiaging-hype

#Science #Longevity #Aging #AntiAging #Supplements #BlueZones

‘Morbid’ doesn’t want you to fall for antiaging hype

Scientist Saul Justine Newman debunks high-profile longevity research and antiaging “medicine” in a new book.

Science News
“Clinically tested” has excellent posture and very little accountability. Tested against what? In whom? For which endpoint? If the label cannot answer that, the lab coat is mostly costume. #Supplements #Science
Source: Lim et al. Nutrients 13(2):661, 2021. Meta-analysis of 18 RCTs in resistance-trained adults. Plant-based and animal-based protein produced equivalent lean mass and strength outcomes when total protein and leucine content were matched. DOI 10.3390/nu13020661.