Fantastic first set of talks for #MicroEvo22 this morning! First gene-gene interactions in microbial community by Fiona Whlean, then the evolution of S. suis to gain virulence and infect new niches (humans!) and why and now role of the capsule in evolution
Alasdair Hubbard
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Lecturer - investigating the evolution of AMR. Interested in all aspects of AMR and drug discovery. Also T1D. All views my own.
Capsule serotype effects genetic transfer (but depends on MGE), sensitivity to phage and adaptions of the cell in Klebsiella #MicroEvo22
S. suis evolution driven by increased pig farming and selling between farms/countries, acquiring increased virulence factors. #MicroEvo22
JessicaMABlairOur new review is out in @NatureRevMicro: Molecular Mechanisms of Antibiotic Resistance Revisited. #WAAW 😃 https://www.nature.com/articles/s41579-022-00820-y
Molecular mechanisms of antibiotic resistance revisited - Nature Reviews Microbiology
In this Review, Blair, Webber and colleagues explore our understanding of the mechanisms of antibiotic resistance, including reduced permeability, antibiotic efflux, modification or alteration of the antibiotic target, modification or destruction of the drug itself, and bypass of metabolic pathways. They also discuss how this information can aid in developing the next generation of antimicrobial therapies.
@zannah_du @zaminiqbal just thought the same just now while checking twitter, mostly corporate accounts tweeting
@zaminiqbal same, hopefully the scitwitter community will mostly move over soon too
Marley is ready and very excited to present his poster at #MicroEvo22 in Manchester on Tuesday!
@lore_fermar Same, the talks looks awesome, can't wait! Hopefully the hashtag will migrate over to here as well
Volker Weber 🎧Just a quick poll. #Boost ok.
Have you been infected with Covid-19?
0 - Not yet
1 - Once
2 - Twice
3+ More than twice
Poll ended at .
Professor Lesley HoylesVery pleased to see this out. Another huge effort from @SimonMcArthur and his research team.
Cerebrovascular damage caused by the gut microbe-derived uraemic toxin p-cresol sulfate is prevented by blockade of the epidermal growth factor receptor https://www.biorxiv.org/content/10.1101/2022.11.12.516113v1