Our new review is out in @NatureRevMicro: Molecular Mechanisms of Antibiotic Resistance Revisited. @lizzy_darby @ilyas_alav @ma_webber @ETrampari @MariaSolsona28 & Pauline @IMIBirmingham @TheQuadram #WAAW 😃 https://www.nature.com/articles/s41579-022-00820-y
Molecular mechanisms of antibiotic resistance revisited - Nature Reviews Microbiology
In this Review, Blair, Webber and colleagues explore our understanding of the mechanisms of antibiotic resistance, including reduced permeability, antibiotic efflux, modification or alteration of the antibiotic target, modification or destruction of the drug itself, and bypass of metabolic pathways. They also discuss how this information can aid in developing the next generation of antimicrobial therapies.