David Schnettler

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Postdoctoral researcher at ETH Zurich. Previously PhD student in the Hollfelder Lab at University of Cambridge. Interested in all aspects of #proteinengineering and #proteinevolution.
Webhttps://usys.ethz.ch/en/people/profile.MjkzNzI2.TGlzdC82MzcsMzIwMTk3MjIy.html
ORCIDhttps://orcid.org/0000-0002-9909-6190

Happy to see our preprint out on #bioRxiv! We screened #denovodesigned proteins for #phosphoesterase activity in #microfluidic droplets – and found truncated peptides that dynamically oligomerise to proficiently break down cAMP! This project from my time at the Hollfelder lab at the University of #Cambridge was a collaboration with the Hecht lab at #Princeton University. Special thanks to Michael Wang (co-first!) and Max Gantz for the wonderful teamwork!

https://biorxiv.org/content/10.1101/2023.02.13.528392v2