Mechanism of conductance control and neurosteroid binding in NMDA #IonChannel receptors | Nature
Sorry it is paywalled…. But look at the beautiful channels 🥲
Channelomics
@channelomics
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We had a successful account on Twitter. Now trying to spread across platforms for longer term sustainability.
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#IonChannels
Deletion of the TRPV1 #Ionchannels attenuates afferent renal nerve responses to renal artery occlusion but not elevated renal pelvic pressure
https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP289721?af=R
Substrate stiffness attenuates cardiomyocyte depolarization slope via sodium channel modulation (Increased stiffness of the substrate causes the dysfunction of Nav1.5 #Ionchannel kinetics) https://www.sciencedirect.com/science/article/abs/pii/S0003986125003820
Sclareol and cinnarizine are non-selective inhibitors of voltage-gated Cav1.3 L-type Ca2+ #ionchannels Open access.
https://www.tandfonline.com/doi/full/10.1080/19336950.2025.2556101
Mouse retinal ganglion cells and night blindness |
TRPM1 #ionchannels, mGluR6 of retinal ON bipolar cells
J.General Physiol. https://rupress.org/jgp/article/157/6/e202413749/278375/A-mechanism-for-pathological-oscillations-in-mouse
Aberrant HCN4 #ionchannel expression: Impacts on neuronal excitability and implications for epilepsy pathogenesis - Spyrou - British Journal of Pharmacology
Paywalled
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70218
Piezo1 #ionchannels regulate the mechanotransduction of soft matrix viscoelasticity | Nature Communications https://www.nature.com/articles/s41467-025-64185-5
Massive reduction of RyR1 #Ionchannel in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis - Ruiz - The Journal of Physiology
https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP287832?af=R
Augmenting AMPA #IonChannel signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery - Nature Neuroscience
Curious… what’s up?
#IonChannels
Expression of Concern https://www.tandfonline.com/doi/full/10.1080/19336950.2025.2570092?af=R
