New paper from the @AnneStraube lab describing their ShapeSpaceExplorer tool to analyse cell shape
Paper: https://doi.org/10.1371/journal.pcbi.1013864
| Website | http://mechanochemistry.org |
New paper from the @AnneStraube lab describing their ShapeSpaceExplorer tool to analyse cell shape
Paper: https://doi.org/10.1371/journal.pcbi.1013864
Calling all #MotorsInQuarantine fans: Please join us for 1.5 days of science on motors and the cytoskeleton as we celebrate the career of Rob Cross. More info and sign-up here:
Anne says: The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.
Rob says:
Sumiyoshi et al. https://pubmed.ncbi.nlm.nih.gov/39012822/ asks, can kinesin heads tethered via surface loops still drive microtubule gliding? Indeed! Scanning a dsDNA tether across all exposed loops reveals a core mechanical cycle of the motor that underlies, and is amplified by, linker docking.
Natural kinesin motors are tethered to their cargoes via short C-terminal or N-terminal linkers, whose docking against the core motor domain generates directional force. It remains unclear whether linker docking is the only process contributing directional force or whether linker docking is coupled …
The Tri-Grid Challenge Term 3 is over!
CMCB Flyers finished in 8th place!!