New work from our lab!
G3BP1-dependent mechanism suppressing protein aggregation in Huntington’s models and its demise upon stress granule assembly

https://academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddac304/6972256?utm_source=advanceaccess&utm_campaign=hmg&utm_medium=email

Here we explored whether stress granules influence Huntington’s disease-related changes. We found that induction of stress granules triggers the accumulation of pathological aggregates in Huntington’s disease models.

@CECAD @UniKoeln