We have an exciting postdoc opening to work on our #ERC synergy project. If you want to go RNA biology at scale combining genomics, synthetic biology and Machine learning. Please apply https://ki.varbi.com/en/what:job/jobID:694437/ deadline 25Feb.
PelechanoLab
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We are a group based in karolinska Institute and SciLifeLab in #Sweden. We love RNA biology, Epigenetics and developing new genomic methods http://pelechanolab.com/ Posts by Vicent Pelechano.
Extremely happy to have been awarded one of this year #ERCSyn grant together with my colleagues Kevin Verstrepen and Julien Gagneur. https://europa.eu/!tBXnmt
European Research Council (ERCR to @ERC_Research: Would you like to see exactly which projects and researchers won 2023 ERC Synergy Grants - each worth around €10 million?
Check the list, you might know someone on it!
@EU_Commission @EUScienceInnov 🇪🇺#FrontierResearch #Teamwork
🐦🔗: https://nitter.cz/ERC_Research/status/1717481293708202136#m
[2023-10-26 10:00 UTC]
We are looking for a postdoc to join our team and continue on our work on metadegradomics (Huch, Nersisyan et al. Nat microbiology 2023). Please apply and join your team at Karolinska Institutet in Stockholm (Sweden).
Postdoctoral Researcher in Computational RNA biology and Metagenomics. Deadline 24th June https://ki.varbi.com/en/what:job/jobID:633155/
Postdoctoral Researcher in Computational RNA biology and Metagenomics. Deadline 24th June https://ki.varbi.com/en/what:job/jobID:633155/
Extremely happy to see our work on #metadegradomics published now in Nature Microbiology. If you want to study ribosome position in hundreds of species from a complex microbiome samples this might be of interest for you :) https://www.nature.com/articles/s41564-023-01393-z
Open #postdoc position in #RNA #genomics to study RNA-protein interaction and subcellular localization at single-cell level. Join us at #KarolinskaInstitutet #SciLifeLab in beautiful #Stockholm. Link here: https://ki.varbi.com/en/what:job/jobID:625439/
Deadline 27 May 2023
Deadline 27 May 2023
Cosmin SaveanuMaster (M2) students interested in the study of #mRNA degradation mechanisms, their conservation and divergence - a new project on Cryptococcus neoformans molecular biology is underway at the Pasteur Institute in Paris (training period starting January 2024):
Thus, our work suggests the existence of coordination between “transcriptional” and “post-transcriptional memory” to facilitate swifter adaptation to changing environments. You can read more here
https://doi.org/10.1038/s41467-023-36586-x
Thanks to all our collaborators #PatriceZeis #LarsSteinmetz #EliskaFurst #Ilaria Piazza et al. And of course thanks to the support that made it possible
Vetenskapsradet, KAWstiftelsen Ragnar Söderbergs foundation
Karolinsak Institutet and SciLifeLab
After discarding chromatin mediated effects, we realised that RNA degradation was differentially regulated in naïve and primed cells. And that this alteration leaded to both faster induction and repression memory in primed cells.
Transcriptional memory is the process by which cells previously exposed to a stimulus respond faster to a second induction. Deletion of factors involved in chromatin organisation and transcription have been shown to decrease transcriptional memory.
We performed a genome-wide screen to identify new factors controlling this process in budding yeast. Surprisingly, we found that the depletion of components of the nuclear RNA exosome INCREASED transcriptional memory.