Mark Potten

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STED #nanoscopy reveals nanoscale rules for #glutamate #receptor organization. Researchers at West Virginia University and Thomas Jefferson University disclosed a robust #synaptic nanoarchitecture of glutamate #receptor #heterotetramers. Read the 📰 in @Nature Communications! @leicamicrosystems

https://www.nature.com/articles/s41467-022-28504-4
Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specific - Nature Communications

Glutamate receptors comprise two obligate subunits and two subunits that confer distinct properties and functions to the specific tetramers, which also localize to distinct synaptic spines. Here, the authors use STimulated Emission Depletion nanoscopy (STED) to provide detailed insights into the spatial organization of glutamate receptor types.

Nature