On natural products, biosynthesis & microbial interactions.
By members of the Biomolecular Chemistry Department @LeibnizHKI
https://t.co/ZhBlwp01vM
Christian's personal posts: @c_hertweck
Bacterial endosymbionts of beneficial soil fungi protect their hosts against micropredators such as fungivorous nematodes with a cytotoxic benzolactone.
We now found that the anthelminthic effect is boosted with a biosurfactant named symbiosin. Although this compound resembles some fungal metabolites, it is also produced by endofungal bacteria.
Our first paper in 2023 🥳
OA in Chemical Science
🔗 http://ow.ly/zBNg50LZazP
#ChemBioSys #NRPS #biosynthesis #lipopeptide #NaturalProducts #symbiosis
Effective protection of soil fungi from predators is crucial for their survival in the niche. Thus, fungi have developed efficient defence strategies. We discovered that soil beneficial Mortierella fungi employ a potent cytotoxin (necroxime) against fungivorous nematodes. Interestingly, this anthelminthic ag