Christine Mordstein

167 Followers
251 Following
218 Posts

RNA aficionado.
codon usage | RNA therapeutics | genome evolution.
Senior Scientist in RNA Technologies.
Opinions my own. 🇪🇺

#RNA #RNAtherapeutics #mRNA #RNAi #codonusage #syntheticbiology #RNArocks

LocationCambridge, UK
Twitter@CMordstein

🚨 We're expanding our #RNA Technologies team at Eleven Therapeutics! 🚨

👉 https://tinyurl.com/RNA11Tx 👈

Come join us as a Senior Scientist and help develop the next generation of #RNA therapeutics! Our science couldn't be more cutting edge so don't miss this opportunity 😎

Please share!

#RNA #RNAtherapeutics #jobalert #hiring #MolecularBiology #MethodDevelopment #Scientist #RNArocks

Eleven Therapeutics on LinkedIn: Senior Scientist - Molecular Biology/ RNA Biology

🔬🌱 Join the Cutting-Edge Team at Eleven Therapeutics in Cambridge, UK! We're seeking a passionate and innovative Senior Scientist to join our RNA…

RT @amydiehl
New: My latest research finds 30 different characteristics of a woman’s identity that turned into points of criticism creating barriers to women’s success. The clear message to women is that—whatever they are—they are “never quite right.” https://www.fastcompany.com/90889985/new-research-reveals-critiques-holding-women-back-from-leadership-that-most-men-will-never-hear

RT @erlichya
It is a true honor to be included in @Calcalistech 's annual list of "50 most promising Israeli start-ups". Of note, @eleventx is the only biotech company that made it to the list!

Kudos to the team for their hard work, innovation, and dedication!

https://www.calcalistech.com/ctechnews/article/hjtwkugx2

The 50 most promising Israeli startups - 2023

With the fall in venture capital investments removing the background noise, this year’s list of the 50 most promising Israeli startups highlights the companies with a real profit model

ctech

RT @zebioengr
Dope paper from the Langer lab: https://www.nature.com/articles/s41587-023-01774-z

Congrats former @pkumd labmate John Daristotle and @UMDBIOE alum @LisaTostanoski !

A microneedle vaccine printer for thermostable COVID-19 mRNA vaccines - Nature Biotechnology

Automated fabrication of microneedle patch mRNA vaccines for COVID-19 may improve vaccine access.

Nature

RT @SlenderSherbet
Me, heading into another week.

#MondayMotivation

NimwegenLab on Twitter

“Hey, weren't you a co-author on that? https://t.co/sDBpU9UPnZ Yes, I was, but the Nature editors neutered the letter to the point that I felt I could no longer in good conscience put my name on it. The most egregious (and final straw for me) was the insistence to change 1/n”

Twitter
RT @NimwegenLab
Hey, weren't you a co-author on that?
https://www.nature.com/articles/s41586-023-05865-4
Yes, I was, but the Nature editors neutered the letter to the point that I felt I could no longer in good conscience put my name on it. The most egregious (and final straw for me) was the insistence to change 1/n
Insufficient evidence for non-neutrality of synonymous mutations | Nature

RT @benoitbruneau
apparently all languages are beautiful when spoken pleasantly https://www.pnas.org/doi/epdf/10.1073/pnas.2218367120
http://www.ncbi.nlm.nih.gov/pubmed/19366666 The most hydrophobic amino acids all have NUN codons and U-content in ORFs tracks with hydrophobicity.
Studying membrane proteins through the eyes of the genetic code revealed a strong uracil bias in their coding mRNAs - PubMed

Posttranscriptional processes often involve specific signals in mRNAs. Because mRNAs of integral membrane proteins across evolution are usually translated at distinct locations, we searched for universally conserved specific features in this group of mRNAs. Our analysis revealed that codons of very …

PubMed

RT @DrMikeBooth
We've topologically constrained antisense oligonucleotides into a handcuff structure, via photocages, to control gene knockdown!

Published in @ChemCommun, led by @DenisHartmann
@OxfordChemistry @OxfordSynthesis @UCLChemistry #supramolecular #ASO https://rsc.li/3zY0vC5

Handcuffed antisense oligonucleotides for light-controlled cell-free expression

Developing simple methods to silence antisense oligonucleotides (ASOs) using photocages opens up the possibility of precise regulation of biological systems. Here, we have developed a photocaging strategy based on ‘handcuffing’ two ASOs to a protein. Silencing was achieved by divalent binding of two terminal