Mastodawn

When a gene is transcribed, it creates physical ripples along the DNA strand that can either activate or suppress neighboring genes. The physical ordering and arrangement of these genes, known as "gene syntax," directly dictates how their structural interactions couple their expression.
#SyntheticBiology #Biophysics #Genetics #ChemicalEngineering #sflorg
https://www.sflorg.com/2026/04/sybi04302601.html

Gene circuits reshape DNA folding and affect how genes are expressed

Discover how gene syntax and physical DNA folding changes, like supercoiling, allow scientists to biophysically control synthetic gene circuits.

Scientific Frontline 4d ago

Synthetic biology is a multidisciplinary area of research that involves the design and construction of novel biological parts, devices, and systems, as well as the re-design of existing, natural biological systems for useful purposes. Its primary goal is to apply rigorous engineering principles to biology.
#SyntheticBiology #Biology #sflorg
https://www.sflorg.com/2026/04/cat04292601.html

Synthetic Biology: In-Depth Description

Synthetic biology matters because it transitions biology from a purely observational and analytical science into a highly applied, synthetic disciplin

Scientific Frontline 5d ago

SMART (Single-Molecule Assay on Ribonucleic acid by Translated product) is an advanced in vitro selection platform designed to accelerate directed enzyme evolution. It significantly reduces the time and cost required to identify superior enzyme variants by tracking them at the single-molecule level.
#SyntheticBiology #MolecularBiology #Biochemistry #Biotechnology #sflorg
https://www.sflorg.com/2026/04/sybi04282601.html

Scientists pave the way for fast, cost-effective custom enzyme development

Enzymes are proteins that catalyze chemical reactions in living organisms

Matthias C. Rillig 6d ago

If you could build a synthetic plant-soil ecosystem from scratch for use on another planet (ignore if this makes sense or not), would it have mycorrhiza?

Explain why or why not... 😀

#ecology #syntheticbiology #soil #mycorrhiza

Big Fl👀f is watching you.Apr 20

Oh my holy rabbit. 300 chars on #BlueSky are so short but lets look maybe it will trigger someone there #Palantir & #KarpManifesto are boring. #BioHacking #SyntheticBiology is the future. https://floof.sbs#09 https://floof.sbs#12 multi-layered bio-cipher to hide messages in DNA using Gaussian bell curves, prime numbers, hydrogen-bond checksums & wobble positions of the code sun. Untraceable for any #LLM. #BioIT

Scientific Frontline Apr 20

Epigenome regulators are specialized proteins bound to DNA that control gene expression not merely as simple on/off switches, but by producing distinct, uniquely patterned behaviors and expression dynamics for specific genes.
#Epigenetics #MolecularBiology #SyntheticBiology #CellularEngineering #sflorg
https://www.sflorg.com/2026/04/epig04202601.html

Study Finds Each Protein in the Epigenome Produces a Different Pattern of Gene Expression

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off

Big Fl👀f is watching you.Apr 19

🧬 // Is it a message or not (Where is Schrödingers cat Director´s Cut)

https://floof.sbs/#12

#DNA #Genetics #SyntheticBiology

🐶 mood 💞 // [email protected]

Bound by paws, guided by spirit. Creating destiny through every high and low.

Matthias C. Rillig Apr 18

If we wanted to put together an artificial ecosystem to maximize one function (let’s say carbon storage), how would we do it?

This is interesting to think about…

https://open.substack.com/pub/matthiasrillig/p/synthetic-ecosystems?r=1yu2t7&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true

#ecology #ecosystem #syntheticbiology

Synthetic ecosystems?

Thoughts on synthetic biology

The Ecological Mind: ecology, research, creativity

Big Fl👀f is watching you.Apr 12

🧬 // Steganographic multi-layered bio-cipher. (Biopunk meets Geopunk Director’s Cut)

„It's a storage format, not just an acid“.

#BioHacking #Biopunk #BioSteganography #Cryptography #Cyberpunk #CyberSecurity #DNA #DNAStorage #Genetics #InfoSec #OpenScience #Science #SyntheticBiology

https://floof.sbs/#09

🐶 mood 💞 // [email protected]

Bound by paws, guided by spirit. Creating destiny through every high and low.

Scientific Frontline Apr 4

The sheer scale of what synthetic biology aims to achieve can often feel indistinguishable from science fiction. We are actively learning to speak the fundamental language of life, not merely to read its ancient history, but to actively write its future.
#SyntheticBiology #MolecularBiology #ComputationalBiology #Genetics #ArtificialIntelligence #sflorg
https://www.sflorg.com/2026/04/wi04042601.html

What Is: Synthetic Biology

The sheer scale of what synthetic biology aims to achieve can often feel indistinguishable from science fiction.