Blake Porter

113 Followers
212 Following
36 Posts
🧠🐁💪🏻💻🎮 Postdoc (he/him) @ Brandeis in the Jadhav lab. Studying the neural mechanism of inferential reasoning. Matlab junkie. Video game enthusiast. Formerly BU and Otago.
G Scholarhttps://scholar.google.com/citations?user=G5j_tUkAAAAJ&hl=en
My websitehttps://www.blakeporterneuro.com/
Prefrontal transthalamic uncertainty processing drives flexible switching
https://www.nature.com/articles/s41586-024-08180-8
#neuroscience
Prefrontal transthalamic uncertainty processing drives flexible switching - Nature

By examining neural responses from tree shrews performing hierarchical decision tasks with rule reversals, the authors identify a thalamocortical mechanism for regulating cognitive flexibility.

Nature
Representational spaces in orbitofrontal and ventromedial prefrontal cortex: task states, values, and beyond
https://www.cell.com/trends/neurosciences/fulltext/S0166-2236(24)00202-9
#neuroscience
@PhiloNeuroScie super cheap, esp compared to their Neuralynx system. Even if you just buy from open ephys:
DAQ: $350
Miniscope v4: $2000
Wirefree converter: $540
Batteries/charger: $100

((Prices are in Euros))
Novel way to study the transition from #goals to habits: motivating animals by palatability rather than biological need. Authors find spontaneous and abrupt transitions to #habits, blocked by dorsolateral striatal lesions. Beyond the classic #devaluation experiment! Awesome ✨stuff by Kuchibhotla lab #neuroscience https://www.biorxiv.org/content/10.1101/2023.07.05.547783v1
Hey Mastodon users! This is my first post as I just opened my account migrating from @doctorpoe on twitter. I hope to find my old friends and make new ones among the mastodon conoscenti.
@elduvelle nah i dont think so, or at least not normal drift. It's been the same for a week now.
@elduvelle it does feel like a property of the individual tetrodes tho, since it tends to be all long oval or all more circular
@elduvelle hmmm im not too sure of that, and i mean that literally. I always thought closer = high voltage, esp since all my electrodes have nearly the same impedance. With that in mind, i definitely get high voltage circular clusters and lower voltage long oval clusters, so im too sure how distance could explain it. maybe it has to do with dist to the axon hillock or soma. Its also a odd that i could be close to 3 neurons w oval clusters and not close to any of the 5 neurons w circular clusters
I sometimes get tetrodes (targeting dCA1) that only have clusters that are massive “long” ovals due to complex spiking (pic 1). While others have more “normal” circular clusters, presumably little cmplx spk (pic 2). Do we know why this is? These TTs are right next to each other
@elduvelle i am still just in complete denial that its time for abstract submission again. I feel like i just submitted the last one yesterday