nyx mirDec 15

Safety Warning for people on Rapamycin / Sirolimus / Rapamune

Chrysanthemum, Dandelion, Bishop's Weed, and/or Liquoirce, even if blended with other tea ingredients, can interact with the medications, including stopping absorption & be potentially dangerous. Please be careful.

For me personally, chrysanthemum tea blocked the efficacy of my latest dose of rapamycin. I'm really hoping that's all that it did.

https://pubmed.ncbi.nlm.nih.gov/24824478/

#LongCovid #MECFS #rapamycin #sirolimus #transplant #polybio #putrinoLab #rapamune #mTorInhibitor #lymphaticMalformation #TuberousSclerosisComplex

Show threadnyx mirDec 15

Medication Interaction Warning Edit:

Liquorice, Dandelion, Bishop’s Weed and Chrysanthemum can impact efficacy and safety of a LOT more medications.

The liver impact they have is because of the same CYP3A4 interaction is the GRAPEFRUIT WARNING. Not medical advice, but if you’ve been warned by a prescriber, pharmacist, or bottle not to have grapefruit (pomelo, bitter orange, certain other fruits), maybe don’t have those herbs until you talk to someone knowledgable.

https://en.wikipedia.org/wiki/Grapefruit%E2%80%93drug_interactions

Grapefruit–drug interactions - Wikipedia

Show threadnyx mir

Additional drug table about herbal tea and medication interactions

https://www.ebmconsult.com/content/pages/medications-herbs-cytochrome-p450-cyp-enzyme-inhibitors

Medication & Herbal Inhibitors of the Cytochrome P450 (CYP) Enzymes Drug Table

Evidence-Based Medicine Consult

Apr 11 at 10:25pmWeb
Show threadforestine2d ago
@NyxMir oh i didn't know that about chrysanthemum!
Show threadclown event still possib-L2d ago
@NyxMir GINGER!?!?!?
Show threadnyx mir2d ago

@ldottxt Check the absorption windows of your meds and you might be able to stagger?

Sirolimus 2x/week only needs 1 hour each dose. I think this means hypothetically I could take chrysanthemum on other days, but buspirone is also CYp3A4 and a 2x every day med so it's not reasonable for me to do that in actuality.