@edd @ascentale @skyfaller @bikenite A7: We've got a front loader cargo bike (a backfiets clone) and my 18 months old daughter travels in the front box, strapped with a 5-point belt to a bicycle child seat. It's similar to the ones used in cars, but smaller. The seat is mounted lower than usual: this leave less space to the legs, but she's more protected by the bicycle box.
Other than that, reflectors adhesive strips and lights always on.
I tend to avoid fast or traffiked roads as much as possible.