RoedigerRG

In 2024, we published a review (https://www.frontiersin.org/articles/10.3389/fnmol.2024.1386735) on miRNAs in #neurodegenerative diseases (including #Parkinson's Disease, #Alzheimer's Disease, Multiple Sclerosis, #Huntington's Disease, and Amyotrophic Lateral Sclerosis). The goal was to collect miRNAs which have statistically significant regulations, based on data from reviewed publications.

With the data, we aim to identify patterns that could aid in detecting these diseases. This is part of our #NeuroMir project (2022–2025).

Frontiers | MicroRNA biomarkers as next-generation diagnostic tools for neurodegenerative diseases: a comprehensive review

Neurodegenerative diseases (NDs) are characterized by abnormalities within neurons of the brain or spinal cord that gradually lose function, eventually leadi...

Frontiers
Feb 3 at 10:44amWeb
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To achieve this, we developed #DynamiR (https://codeberg.org/a_probst/DynamiR).

DynamiR a Python-based open-source tool with minimal dependencies, making it easy for anyone to analyze independently.

It's built on open data and decentralized, ensuring flexibility and adaptability.

#miRNA #NeurodegenerativeDiseases #ResearchUpdates #OpenScience #SoftwareDevelopment #PD #ALS #HD

DynamiR

Public depository for the DynamiR project.

Codeberg.org