@patrick_h_lauke This almost certainly is caused by the (color profile of the) monitor you're using.
I can't replicate it on my (stock) windows machine with Chrome's eyedropper running in Polypane.
Indeed: If color management is enabled (on any system, Win/Mac/Lix) the dropper may provide unpredictable results. Choosing a default sRGB profile while using the picker may help mitigate issues.
Better to use a stand alone dropper tool that is color management aware.
For MacOS, that's "Classic Color Meter" desktop app.
Discussion and best practices in our draft guidelines:
https://readtech.org/ARC/tests/visual-readability-contrast/?tn=methods#tool-setup
@darrell73
By "color picker" he means a tool that looks like an eyedropper which gets a color value not from the web code but from the system doing visual rendering for the operating system.
I've encountered this problem on my MacBook with both Firefox and Chrome. When the browser window is in the built-in display, the picker gets accurate colors but on my HP monitor, they're sometimes inaccurate.
It's a little surprising for the tool within the browser's DevTools to have the problem but the aim is still to capture the perceived color value, even if there are multiple layers of differently colored objects with different levels of opacity.