Julie WebgirlSo I'm curious. What are your current #Covid mitigations?
Boost (no pun intended) for better numbers š
Nothing / outdated vaccine
Vaccine + latest boosters
Mask + vaccine + latest boosters
Mask ONLY
Poll ended at .
Jeremy List@juliewebgirl I'm about due for another booster shot. Still masking.
DB SchweinMasking in medical places/travel, and tracking wastewater levels in case that needs to change.
_Plus:
staying at home,
click and collect groceries,
riding around the lake instead of going to a gym.
@arose62
I've never heard the term "click and collect" before. Here in the US it's "curbside delivery".
I've never heard the term "click and collect" before. Here in the US it's "curbside delivery".
Australian usage strikes:
"Home delivery" - as it sounds
"Click and collect" - place order online, then drive to a designated parking spot near the store, and they bring your purchases out to you.
"Direct to boot" - like click and collect, but you don't get out of the driver's seat; they actually put your purchases into your car boot.
@arose62
Ahh, thanks. Here is the same with home delivery. Our curbside is your direct to boot. Oh I guess there's also "pick up in store" where you order online and then go inside to a special counter to pick it up. That one defeats the purpose as far as I'm concerned.
Ahh, thanks. Here is the same with home delivery. Our curbside is your direct to boot. Oh I guess there's also "pick up in store" where you order online and then go inside to a special counter to pick it up. That one defeats the purpose as far as I'm concerned.
Frank Heijkamp@juliewebgirl Avoid 'too' big crowd's and mask up in tight spaces like bus or plane.
Jay@juliewebgirl Voted 3, with the caveat that while I, at personal request, was able to get the latest booster, itās not always available unless youāre in a āhigh riskā group.
I am in a high risk group every time Iām around people whose medical histories arenāt tattooed to their faces and since Iād rather not -literally kill them- I also mask.
And avoid crowds. But thatās more of a personality thingā¦
Arthur van der Harg@juliewebgirl My immunity has just been updated by an infection, kind of like a natural booster. I suppose Iām good for the next 1.5-2 years.
sabik@ArtHarg @juliewebgirl
Unfortunately, as I understand it, immunity from infection is at best partial and fleeting, what with swiftly-changing variants and the damage covid directly does to the immune system š
Unfortunately, as I understand it, immunity from infection is at best partial and fleeting, what with swiftly-changing variants and the damage covid directly does to the immune system š
@sabik @juliewebgirl Thatās not how it works. COVID does not damage the immune system. What you see is the after effects of the IS having fought a viral infection. Like an empty supermarket shelf at the end of day: it will be refilled.
What lasts a couple of months is antibodies. But an infection also updates memory B cells. Those are the ones that churn out antibodies the next time youāre infected. So the infection is still fought much quicker than before immunity.
Sure: @marc_veld is an actual immunologist (I am not) who explains the immunology of COVID quite well. I've been following him since the early days of the pandemic. Scan his timeline, you'll find plenty of articles. (Note: some people find his style of writing somewhat abrasive. I've seen some of the cr** he's been dealing with on Twitter, so I understand where he's coming from.)
@ArtHarg
I asked for a link not a timeline to spend hours scrolling looking for one data point.
@sabik @marc_veld
I asked for a link not a timeline to spend hours scrolling looking for one data point.
@sabik @marc_veld
@juliewebgirl @sabik @marc_veld The workings of the immune system and its response to SARS-CoV-2 are not one single data point. But (showing my reasonable, helpful side): what information would you like to find at any link I provide?
@ArtHarg @juliewebgirl @marc_veld
SARS-CoV-2 Reinfection and Severity of the Disease: A Systematic Review and Meta-Analysis
> Reinfection with SARS-CoV-2 suggests that natural immunity is not long-lasting in COVID-19 patients.
SARS-CoV-2 Reinfection and Severity of the Disease: A Systematic Review and Meta-Analysis
Since the discovery of SARS-CoV-2, changes in genotype and reinfection with different variants have been observed in COVID-19-recovered patients, raising questions around the clinical pattern and severity of primary infection and reinfection. In this systematic review, we summarize the results of 23 studies addressing SARS-CoV-2 reinfections. A total of 23,231 reinfected patients were included, with pooled estimated reinfection rates ranging from 0.1 to 6.8%. Reinfections were more prevalent during the Omicron variant period. The mean age of reinfected patients was 38.0 Ā± 6. years and females were predominant among reinfected patients (M/F = 0.8). The most common symptoms during the first and second infection were fever (41.1%), cough (35.7% and 44.6%), myalgia (34.5% and 33.3%), fatigue (23.8% and 25.6%), and headaches (24.4% and 21.4%). No significant differences of clinical pattern were observed between primary infection and reinfection. No significant differences in the severity of infection were observed between primary infection and reinfection. Being female, being a patient with comorbidities, lacking anti-nucleocapsid IgG after the first infection, being infected during the Delta and Omicron wave, and being unvaccinated were associated with a higher risk of reinfection. Conflicting age-related findings were found in two studies. Reinfection with SARS-CoV-2 suggests that natural immunity is not long-lasting in COVID-19 patients.
@sabik @juliewebgirl @marc_veld Yeahā¦ wellā¦ the trouble with these systematic reviews and meta-analyses is that it is very easy to make methodological errors. Here, for instance, they rely on RT-PCR. There must be a reason to perform RT-PCR, so there is a significant selection effect in the groups that they study. And then we come to the following (esp. part 5/5): https://mastodon.online/@marc_veld/112649318254831164
Marc Veldhoen (@[email protected])
Protective effectiveness of previous infection against subsequent SARS-Cov-2 infection: systematic review and meta-analysis I see very wrong messaging about this paper. Infection-immunity works, of course, also against SARS-CoV-2. https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1353415/full 1/5
@juliewebgirl @sabik @marc_veld Confirmed: twice, and I suspect that I've also had it in the very early stages of the pandemic, before testing was generally available. First confirmed time was in between the first and second booster shots and the second confirmed time was roughly a year and a half after the second booster.
And how about yourself?
@ArtHarg @juliewebgirl @marc_veld
As for immune system damage, it's one of the items in long covid
See e.g. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839201/
Long COVID: major findings, mechanisms and recommendations
Long COVID is an often debilitating illness that occurs in at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms have been identified with impacts on multiple organ systems. At least 65 ...
@sabik @juliewebgirl @marc_veld True, the immune system is disrupted in a certain fraction of long covid cases. But AFAIK the jury is still out on whether this is actual damage or just an immune system that cannot completely clear a SC2 infection and is exhausted. And also whether the immune system of some individuals causes this, or SC2 can cause this in anyone. That makes a difference in the risk of long covid with repeated infections.
Insecurity Princess ššš„@ArtHarg are you an immunologist?
@saraislet No, but @marc_veld is and that is where I get my information from.
Joe Cooper šŗš¦ š@juliewebgirl still masking in crowded indoor spaces. I work from home, and most of my hobbies are outdoors, so I can avoid crowded indoor spaces most days. Also, up to date on vaccines.
Emily King@juliewebgirl in the UK, despite being eligible for previous rounds of NHS led vaccinations, the government has decided I'm now in a group not eligible for the latest booster. And the cost (Ā£99+) and distance (80+ miles) means that I can't go and get a booster privately.
Q. Pheevr@juliewebgirl
N95 masks in all indoor public spaces; vaccine plus all the boosters the province of Nova Scotia will give me
N95 masks in all indoor public spaces; vaccine plus all the boosters the province of Nova Scotia will give me
Stuart 
@juliewebgirl I had the vaccine, two boosters and use a mask. But I haven't been eligible (here in the UK) to get more recent boosters being under the age the government allows for them on the NHS.
utility himbo@juliewebgirl Outdated vaccine (all my country will let me have) and masks.
Åukasz 
@juliewebgirl just fyi: some countries (like the UK) donāt allow people to get boosters at all (even if you want to pay), except for people in the risk groups
Muro deGrizecoI wear 3M Aura #N95 masks in all public indoor spaces, like work or stores.
My family goes into precaution mode if we've had an exposure or someone is sick. We mask and force airflow through the house.
We have each been vaccinated and get boosters as we can. We will continue.
When 2 of my family got covid, we rushed to get them Paxlovid.
We know of people injured by #COVID
We know those who died.
Denial and minimization are warfare.
Urzl
AccordionBruce@juliewebgirl @catsalad
Little co2 meter tells me when masking is most needed
So I donāt usually wear one in wide open places where thereās few people