Fascinating footage of a human white blood cell chasing a bacterium captured through a microscope.

Credit: David Rogers

https://embryology.med.unsw.edu.au/embryology/index.php/Movie_-_Neutrophil_chasing_bacteria

#health #biology #science #phagocytosis

@wonderofscience hang on a sec, downloading the source code for Liquid wars for some minor modification...
@wonderofscience One question, tho. How does the bacterium "know" it's being chased? In fact, is the white blood cell really chasing the bacterium? Or just following a trail of something? Are they sensitive to touch? How does the white cell determine that it has to eat something?

@yuki2501 @wonderofscience I'd wager that there's a T or B cell developed protein attached to the bacteria that the white blood cell is able to follow once it detects the chemical signal nearby.
https://www.scientificamerican.com/article/how-do-white-blood-cells/

As to why it continues to follow that bacterium and appear to ignore the other one (if it was also tagged), I'd say it's analogous to how genetic algorithms work to come to a local maximum based on random chance input (my specialty is Comp Sci).

How do white blood cells recognize invaders?

Scientific American

@zecuse @yuki2501 @wonderofscience to detect it wouldn't there have to be a "smell", a gradient of concentration of some molecule?

If it's just a single protein attached, how is it "detected" remotely?

@yuki2501 chemotaxis..white blood cells are attracted to bacteria because of toxins secreted by them or when it comes to inflammation substances secreted by the wounded cells @wonderofscience
@yuki2501 @wonderofscience Looks like the bacteria is just being pushed away, it doesn't know it's being chased and doesn't flee.
@wonderofscience I feel like we’d all respect and treat our bodies a little better if we all saw this!
@wonderofscience Huzzah! The bacterium is toast! White blood cell for the win!
@wonderofscience j'ai cru qu'il ne l'attraperait jamais ><
@wonderofscience it got him in the end! That's the dedication of the immune system, right there ❀️
@wonderofscience Needs s sound track; maybe the Benny Hill theme song.

@Albatrossity @wonderofscience

I was thinking "Bad Boys (whatcha gonna do)" - like it's an episode of Cops.

@wonderofscience
Now, THAT is just beautiful! Chemotaxis and cytoskeleton tour de force!
@wonderofscience this needs the Star Trek fight music
Wow, β€˜white blood cell’ sounds so innocent, but that thing is a tenacious predator!
@wonderofscience I am so very happy this account migrated from the avian droppings container.
@wonderofscience I cheered mentally when it caught the bacteria 🀣
@wonderofscience Jamie Raskin diagnosed with lymphoma are these white blood cells what he needs?
@wonderofscience anyone else got the music from β€œJaws” in their head?
@wonderofscience It’s a fantastically satisfying clip to watch!
@wonderofscience I hear Pac Man sounds while watching this...
@wonderofscience Our bodies are insane! 🀩
@wonderofscience @viridian I watched this over and over - mesmerising 😯

@wonderofscience

OK, the alt text cracks me up: β€œAmorphous blob chasing a dumbbell shaped speck.”

Aren’t we all sometimes just amorphous blobs?
… except when we’re dumbbells?

πŸ˜†

@wonderofscience You can imagine the Charlie Brown-like scream when the macrophage catches up to it.

@drwho @wonderofscience

Funny. πŸ™‚
I heard The Wilhelm Scream. 😱

@wonderofscience β€œout of my way, red boy!”
@wonderofscience "You will be assimilated into the borg."
@wonderofscience >> WoW, that is fascinating. Never seen that before. Thanks for the share. 😁
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@wonderofscience Always bet on the shoggoth.
@wonderofscience It looks so much like Slither.io! Very cool!

@wonderofscience Intelligence in a cell ❀ You GO cell, get that sicko!

I suddenly think of a book in which we one day discover that all our cells have intelligence?
And that cells develop the capacity to revolt if you don't take good care of your body πŸ€”
I would read that book!

@pascaline Blood Music by Greg Bear is a great take on this, only we ~give~ our cells intelligence.

@wonderofscience

@Kencf618033
Oh, thank you, I like Greg Bear!
I didn't know that one yet. Now I am curious 😊

@wonderofscience

@wonderofscience

Perhaps the bacterium was pushed from start to finish.

And the white blood cell? The chase was not consciously motivated, the catch was not consciously satisfying, and the episode went unremembered.