Cheryll1950Dec 5, 2022
Eric Topol
Covid is associated with a >60% increased risk of newly diagnosed diabetes
A systematic analysis replicated by 2 independent groups
https://nature.com/articles/s41598-022-24185-7…
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02656-y…
Dec 5, 2022 at 12:41amWeb
Show threadKate CrawfordDec 5, 2022
@erictopol staggering to think how all this is going to play out over the next 10 years.
Show threadBrian DeViteriDec 5, 2022
@erictopol Awful. The general immune system being activated by COVID infection seems to trigger so many predisposed and related inflammatory conditions.
Show threadNina SteeleDec 5, 2022
@erictopol we need to be studying impact of COVID on the human pancreas! 😥 why is not one talking about this?!?!
Show threadmmalcDec 5, 2022

@erictopol

At this point, would it not be easier to list the maladies that are unlikely to be made more likely and/or more severe following Covid?

I’m fairly sure that if I did get it I wouldn’t be any more susceptible to developing an ingrowing toenail, but that’s about all

Show threadAskPippa🇨🇦Dec 5, 2022
@erictopol What portion of those were patients whose diabetes was undiagnosed before they got COVID? This other study found that over 34% of people hospitalized for COVID19 who had diabetes heard about the diagnosis for the first time (that's 8.7% of all the hospitalized patients who were newly diagnosed with diabetes).
https://pubmed.ncbi.nlm.nih.gov/35704430/
HbA1c measurement may save COVID-19 inpatients from overlooked diabetes - PubMed

Diabetes is a predictor of COVID-19 aggravation. Furthermore, in COVID-19 patients with diabetes, high HbA1c levels are a risk factor for severe COVID-19. A total of 8.7% of COVID-19 inpatients were diagnosed with diabetes after HbA1c was measured on admission. Therefore, it is important to measure …

PubMed
Show threadDiane HallinenDec 5, 2022
@AskPippa @erictopol I guess to answer your question we can compare the incidence of newly diagnosed DM in influenza patients in 2018-2019 to newly dx DM pts with Covid in 2020-2021. The variant might matter. I’ve seen some pretty fast progression of DM in young people post Covid. Struck me as weird.
Show threadR Provost, PhDDec 5, 2022

@erictopol

>60% increase in diabetes after Covid-19 is surprisingly bad.

Show threadIgor Rad🇺🇦🇺🇦🇺🇦Dec 5, 2022
@erictopol no thanks
Show threadriverDec 5, 2022
@erictopol some of the normans are trying to live in a state of ignorant bliss but they’re about to have a rude awakening. And to think we have people who are covid deniers in office today.
Show threadToxteth O'GradyDec 5, 2022
@erictopol Since I'm already there, I would hope it won't make my diabetes worse...
Show threadviqDec 5, 2022
@toxtethogrady @erictopol it very well may, in at least two ways:
1) Further disregulation of already messed up metabolism (e.g. "type 1? Why not have insulin resistance as a bonus?")
2) Triggering (further) auto-immune diseases. Hashimoto / psoriasis / rheumatoid arthrisis anyone?
Show threadviqDec 5, 2022
@toxtethogrady @erictopol not to mention the usual dance of "illness causes elevated sugar levels / elevated sugar levels make it harder to fight infection"
Show threadTechno NekoDec 5, 2022

@erictopol
Been struck by the different issues that arise from reinfections as well.
“A study suggests people who catch covid-19 at least twice have double the risk of dying from any cause and are three times as likely to be hospitalised in the next six months, compared with people who test positive just once.”

https://www.newscientist.com/article/2326274-covid-19-what-are-the-risks-of-catching-the-virus-multiple-times/

Covid-19: What are the risks of catching the virus multiple times?

A study suggests people who catch covid-19 at least twice have double the risk of dying from any cause and are three times as likely to be hospitalised in the next six months, compared with people who test positive just once

New Scientist
Show threadPeggyJoan ☮️💙🌈🐶Dec 5, 2022
@erictopol
I had no idea! Although vaxxed and boosted, Covid got me and I lost much of my hearing. I consider myself fortunate.
Show threadLaura LeeDec 5, 2022
@erictopol my friend (vaxxed & boosted) had a “mild” case of covid this past May. In Oct she was hospitalized for acute necrotizing pancreatitis. Now MRI is showing a mass in her pancreas. (Biopsy scheduled for this week). None of her doctors thus far are willing to entertain the possibility that this is related to her prior covid infection, even though she has none of the usual risk factors for pancreatic disease.
Show threadJust EllaDec 5, 2022
@erictopol Whoa!! Is that stat for those pre-diabetics or for the normal blood sugar population. Interesting statistics
Show threadAgatha Bagshot 🖤🌈🖤Dec 5, 2022
@erictopol yes, I can relate to this outcome. Two #covid infections have led to #LongCovid unable to exercise properly, weight gain, the start of diabetes and a number of other health issues.
Show threadchetsimagesDec 5, 2022

@erictopol

Anyone who's taking a statistics course in college knows that association does not mean that one factor caused the other.

Show threadJohan OlofssonDec 5, 2022

Unscientific anecdote:

In March 2020, our cat, then nine years old, seemed to have been infected by me.

The symptoms were right: The cat sneezed, a lot, and slept away a couple of weeks on my lap, which she never had done before. Afterwards I discovered that she'd started drinking much more water than before, and the amount of urine in the litter box is noticeably larger.

Since then, both of us have become considerably weaker and older.

#cat
#Covid
#DiabetesMellitus

@erictopol

Show threadGeoff WinklessDec 5, 2022
@jmo @erictopol have you had her kidney function checked?
Show threadDr. Scott Krugman Dec 5, 2022
@erictopol Something we noticed early on in 2020 anecdotally, good to see data!
Show threadphiltor 🇺🇦🌻Dec 6, 2022
@erictopol Any idea how this compares to flu or other viruses?