After years of development, Tim Henkes "Syndace" has released python-omemo, An open Python implementation of the OMEMO Multi-End
Message and Object Encryption protocol!
It supports legacy OMEMO (aka OLDMEMO) and current state of the art OMEMO:2 (aka TWOMEMO).
Read the full announcement at https://mail.jabber.org/pipermail/jdev/2022-November/090468.html
Congratulations!