Renin, secreted by the kidneys, is essential for #BloodPressure regulation and #FluidBalance by initiating the #RAAS cascade. Learn how it converts angiotensinogen to angiotensin I and impacts #KidneyFunction and #Endocrinology.
Follow nephrology experts for insights: @ASN_Kidney, @NephJC, @Neph_SIM
https://mymedschool.org/portfolio/m04-03-008-renin/?utm_source=mastodon&utm_medium=jetpack_social
Explore Renin, the key enzyme secreted by the kidneys that triggers the renin-angiotensin-aldosterone system (RAAS). Understand its role in regulating blood pressure, fluid balance, and kidney function in health and disease.
Lisa Steinhelfer and Friederike Jungmann found that certain #cancertherapies can cause early #kidneydamage, detectable via #AI-analyzed #CTscans. This allows timely treatment adjustments: http://go.tum.de/787388
#cancertreatment #kidneyfunction
📷A.Eckert
Forever Chemicals May Damage Kidney Function, Evidence Shows : ScienceAlert…
Forever chemicals are falling in the rain, running through our waterways, and swimming in our bloodstreams, and now, initial research suggests these potentially harmful pollutants are 'clogging up' a crucial drainage system in our bodies... Science Alert #health #medicalresearch #kidneys #pollutants #kidneyfunction
Scientists find people who live past 90 have differences in their blood | indy100
https://www.indy100.com/science-tech/blood-differences-long-life
#Age
#Centenarians
#Blood
#Creatinine
#Glucose
#KidneyFunction
#UricAcid
Centenarians have become the fastest-growing demographic group in the world, with numbers approximately doubling every 10 years since the 1970s.Many researchers have sought out the factors and contributors that determine a long and healthy life. The dissolution isn't new either, with Plato and Arist...
cool case discussion on #GFR in people with #Black ethicities in UK
#KidneyFunction
https://www.bmj.com/content/380/bmj-2022-073353.short?rss=1
$gated of course
Interesting as Europe = we don't like CKD-EPI, we prefer EKFC
NICE = CKD-EPI 2009 without race correction
### What you need to know A 37 year old man attends his GP for a review of his blood pressure. He was born in the UK, and his parents are from Nigeria. He was last reviewed three years ago, soon after being diagnosed with essential hypertension, and had been given lifestyle advice and prescribed amlodipine 5 mg daily. An estimated glomerular filtration rate (eGFR) adjusted for ethnicity was 75 mL/min/1.73 m2 (serum creatinine 114 μmol/L), and urinary albumin creatinine ratio (ACR) was 2 mg/mmol. His chronic kidney disease (CKD) classification was G2A1 (low risk of adverse outcomes). Today, his blood pressure averaged 145/90 mm Hg across three readings. He has been taking 5 mg amlodipine regularly. His eGFR is calculated without an ethnicity adjustment to be 58 mL/min/1.73 m2 (serum creatinine 140 μmol/L). Clinical examination is unremarkable. A urine dipstick analysis shows no blood and 2+protein, and a urinary ACR identifies progression to macroalbuminuria (37 mg/mmol). An ultrasound scan of the urinary tract, electrocardiogram, and prostate specific antigen (PSA) test are normal. Chronic kidney disease (CKD) with proteinuria is a stronger predictor of cardiovascular events than diabetes, leading to significant morbidity and mortality.123 There is substantial inequality in CKD outcomes and clinical coding for people of black, Asian, and minority ethnicities in the UK.4 In August 2021, updated CKD …
All Scientifical
mymedschool
Technische Universität München
formuchdeliberation
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Swapnil Hiremath 
MD