Came for the beautiful visuals, stayed for the cheeky name
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RT @abhi_aggarwal1
iGluSnFR3 is published! Check it outβ¬οΈ
https://www.nature.com/articles/s41592-023-01863-6
We made a new glutamate indicator with improved sensitivity, kinetics & localization for imaging synaptic transmission.
This is #iGluSnFR3 in action detecting minis w/ TTX.
@PodgorskiLab @HHMIJanelia @AllenInstitute
https://twitter.com/abhi_aggarwal1/status/1654141541215084545
Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission - Nature Methods
iGluSnFR variants with improved signal-to-noise ratios and targeting to postsynaptic sites have been developed, enabling the analysis of glutamatergic neurotransmission in vivo as illustrated in the mouse visual and somatosensory cortex.
