We've had advances in green genetically encoded Ca2+ indicators (GECIs), but what about red-shifted GECIs? @piatkevichl &co present SomaFRCaMPi, a new soma-localized red #GECI that exhibits improved accuracy & sensitivity for in vivo neuronal imaging @PLOSBiology https://plos.io/3YnCqRW
A sensitive soma-localized red fluorescent calcium indicator for in vivo imaging of neuronal populations at single-cell resolution
Despite recent advances in green genetically encoded calcium indicators (GECIs), developments in red-shifted GECIs have been slower. These authors engineer a new soma-localized red GECI called SomaFRCaMPi that exhibits improved accuracy and sensitivity for in vivo neuronal imaging.



