TUM Global Postdoc Fellowship - TUM

Camarria Williams: Eighth-Grader Discovers Cancer-Fighting Compound in Goose Poop

At just 13 years old, Camarria Williams, an eight-grader has taken the world by storm with her remarkable scientific discovery.

How storage post sampling influences the stability of sebum when used for mass spectrometry metabolomics analysis? - Scientific Reports

Sebum is a biofluid excreted by sebaceous glands in the skin. In recent years sebum has been shown to contain endogenous metabolites diagnostic of disease, with remarkable results for Parkinson’s Disease. Given that sebum sampling is facile and non-invasive, its potential for use in clinical biochemistry diagnostic assays should be explored including the parameters for standard operating procedures around collection, transport, and storage. To this aim we have here investigated the reproducibility of mass spectrometry data from sebum in relation to both storage temperature and length of storage. Sebum samples were collected from volunteers and stored for up to four weeks at a range of temperatures: ambient (circa 17 °C), −20 °C and −80 °C. Established extraction protocols were employed and samples were analysed by two chromatographic mass spectrometry techniques and data investigated using PCA, PLS-DA and ANOVA. We cannot discriminate samples as a function of storage temperature or time stored in unsupervised analysis using data acquired via TD–GC–MS and LC–IM–MS, although the sampling of volatiles was susceptible to batch effects. This study indicates that the requirements for storage and transport of sebum samples that may be used in clinical assays are less stringent than for liquid samples and indicate that sebum is suitable for remote and at home sampling prior to analysis.

P-based referencing for correcting tissue artifacts in laser ablation-inductively coupled plasma-mass spectrometry imaging of cancer samples

Abstract. A referencing strategy based on the element P is presented to compensate for cryosectioning tissue artifacts in laser ablation-inductively couple

Nominierungen für den Johanna-Mestorf-Preis 2025 gesucht

Anlässlich der Kiel Conference 2025 werden herausragende Dissertationen im Bereich der sozial-ökologischen Forschung und der Landschaftsarchäologie ausgezeichnet.