Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics

Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype can be rescued by mutations in the retrotransposon coding sequence.

Nature

New in #VirusLikeParticles for #MucosalVaccination: Macromolecular surface X-linking overcomes mucosal stress factors.

https://doi.org/10.1021/acsnano.3c10339

#science #biomedicalresesrch #vaccination

Initial results from a clinical trial show an experimental vaccine produces immune responses in healthy adults against Covid-19 variants and a range of other coronaviruses.

https://sciencebusiness.technewslit.com/?p=45257

#News #Press #Science #Business #Vaccine #SARSCoV2 #Covid19 #Coronavirus #Variants #Biotechnology #VirusLikeParticles #ClinicalTrial #Canada #Bats #Pangolins

Trial Shows Broad Coronavirus Immune Response

Initial results from a clinical trial show an experimental vaccine produces immune responses in healthy adults against Covid-19 variants and a range of other coronaviruses.

Science and Enterprise