PLOS BiologyAug 19, 2024
#Cdifficile is mainly treated with #vancomycin, so why is resistance not yet a problem? @BuddleJess @BrockhurstLab @RobFagan &co identify 2 resistance pathways that evolve rapidly but with fitness costs that could affect transmission #AMR #PLOSBiology https://plos.io/3YNHS1m
Identification of pathways to high-level vancomycin resistance in Clostridioides difficile that incur high fitness costs in key pathogenicity traits

Clostridioides difficile is a human pathogen primarily treated with the antibiotic vancomycin. High-level vancomycin resistance is a serious problem in other pathogens, not yet for C. difficile. This study identifies two resistance pathways in C. difficile, which evolve rapidly but with fitness costs that could affect transmission.

micrordtMay 3, 2024

Antibiotics Those Inhibit Cell Wall Synthesis

#Ampicillin, #Bacitracin, #Bacteria, #Cephalosporins, #Cycloserine, #GramNegative, #GramPositive, #Penicillins, #Vancomycin #Microbiology Among the antibiotics whose antimicrobial action is by inhibition of biosynthesis of peptidoglycan cell-wall structure are the penicillins, cephalosporins, cycloserine,…. Medical Microbiology & Recombinant DNA Technology (RDT) Labs | Read More -

https://micrordt.wordpress.com/2024/05/03/antibiotics-those-inhibit-cell-wall-synthesis/

Antibiotics Those Inhibit Cell Wall Synthesis

#Ampicillin, #Bacitracin, #Bacteria, #Cephalosporins, #Cycloserine, #GramNegative, #GramPositive, #Penicillins, #Vancomycin #Microbiology Among the antibiotics whose antimicrobial action is by inhi…

Medical Microbiology & RDT Labs
scinexx - das wissensmagazinDec 6, 2023
Ur-Antibiotikum wiedererweckt. Genmanipulierte Bakterien produzieren die rekonstruierte Urform von Vancomycin und Co. #Antibiotika #Antibiotikum #Vancomycin #Paleomycin
https://www.scinexx.de/news/medizin/ur-antibiotikum-wiedererweckt/
Ur-Antibiotikum wiedererweckt

Antibiotische Zeitreise: Forschende haben erstmals rekonstruiert, wie der "Urahn" einer gängigen Antibiotikaklasse aussah – die einst von Urzeit-Bakterien

scinexx | Das Wissensmagazin
Phys.orgMar 7, 2023

Referenced link: https://medicalxpress.com/news/2023-03-combination-therapy-vancomycin-resistant-bacteria.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-combination-therapy-vancomycin-resistant-bacteria.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1633103226051387392#m

RT by @physorg_com: Researchers develop novel combination therapy for treating #vancomycin-resistant bacteria @ScienceAdvances https://www.science.org/doi/10.1126/sciadv.add9280 https://medicalxpress.com/news/2023-03-combination-therapy-vancomycin-resistant-bacteria.html

Researchers develop novel combination therapy for treating vancomycin-resistant bacteria

Researchers have developed a novel combination therapy using an anticancer agent, mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating bacteria that are resistant to the vancomycin, which is also known as vancomycin-resistant Enterococcus faecalis (VRE). The therapy uniquely targets both VRE and the host, stimulating the host immune system to more effectively clear bacterial infections and accelerate infected wound healing.

Medical Xpress