preLightsFind out how genome loci are anchored to the nucleolus! β
Exciting new #preprint from #Trono_Lab shows that ZNF274 competes with CTCF to keep H3K9me3 silenced genome at the nucleolus periphery, fine-tuning cell-specific gene expression.
First preLights post from Silvia Carvalho! β¬οΈ π
#preLight π https://prelights.biologists.com/highlights/clusters-of-lineage-specific-genes-are-anchored-by-znf274-in-repressive-perinucleolar-compartments/
Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments - preLights
Find out how genome loci are anchored to the nucleolus! Exciting new study from @Trono_Lab shows that ZNF274 competes with CTCF to keep H3K9me3 silenced genome at the nucleolus periphery, fine-tuning cell-specific gene expression