Excited to share our collaborative study, now out in Nature Communications:
Astrocyte diversity in the cortex arises from two molecularly distinct radial glia lineages.

A beautiful piece of work from Riccardo Bocchi’s lab at the University of Geneva, with Jiafeng Zhou as first author. My lab contributed to the lineage tracing efforts using TrackerSeq.

Read here: https://www.nature.com/articles/s41467-025-61829-4

#NewsMayerlab #TrackerSeq

Dual lineage origins contribute to neocortical astrocyte diversity - Nature Communications

Astrocytes display diverse molecular and functional features in the brain, but the developmental origins of this heterogeneity are not well understood. Here, the authors show that two separate progenitor types give rise to distinct cortical astrocyte subtypes with specialized roles.

Nature