The beautiful #preprint from Gabriele Ciceri and team #StuderLab reveals why human neurons mature so slowly. Their protocol allows the differentiation of hPSC into a pure population of cortical #neurons and the detailed characterisation of #maturation stages.

Elisenda Raga Gil and Ines Jmel-Boyer from the Life Sciences PhD Students' Association #PiCLS #UniversityofDundee highlight this work in their first #preLight. 📜👀

https://prelights.biologists.com/highlights/an-epigenetic-barrier-sets-the-timing-of-human-neuronal-maturation/

#development #neuroscience #epigenetics